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Titolo:
Value of limited necropsy in HIV-positive patients
Autore:
Guerra, I; Ortiz, E; Portu, J; Atares, B; Aldamiz-Etxebarria, M; De Pablos, M;
Indirizzi:
Hosp Txagorritxu, Dept Anat Patol, E-01009 Vitoria, Alava, Spain Hosp Txagorritxu Vitoria Alava Spain E-01009 -01009 Vitoria, Alava, Spain Hosp Txagorritxu, Dept Internal Med, E-01009 Vitoria, Alava, Spain Hosp Txagorritxu Vitoria Alava Spain E-01009 -01009 Vitoria, Alava, Spain Hosp Txagorritxu, Dept Clin Microbiol, E-01009 Vitoria, Alava, Spain Hosp Txagorritxu Vitoria Alava Spain E-01009 -01009 Vitoria, Alava, Spain
Titolo Testata:
PATHOLOGY RESEARCH AND PRACTICE
fascicolo: 3, volume: 197, anno: 2001,
pagine: 165 - 168
SICI:
0344-0338(2001)197:3<165:VOLNIH>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACQUIRED-IMMUNODEFICIENCY-SYNDROME; AUTOPSY PATTERNS; CITY; AIDS; POSTMORTEM; POPULATION; INFECTION;
Keywords:
AIDS; autopsy; limited autopsy; needle biopsy; Tru-Cut needle; pathology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Guerra, I Hosp Txagorritxu, Dept Anat Patol, Avda Jose Achotegui,S-N, E-01009 Vitoria, Alava, Spain Hosp Txagorritxu Avda Jose Achotegui,S-N Vitoria Alava Spain E-01009
Citazione:
I. Guerra et al., "Value of limited necropsy in HIV-positive patients", PATH RES PR, 197(3), 2001, pp. 165-168

Abstract

We performed limited autopsy with histological examination of tissue coresobtained percutaneously using the Tru-Cut needle and the Jamshidi trocar in 150 adult HIV-positive patients. Data were compared retrospectively with the antemortem clinical diagnosis. Eighty-one percent of the patients were male, and 78% were intravenous drug users. Specimens were obtained from thebrain, liver, lung, bone marrow, and kidney of most patients. The main findings included liver cirrhosis in 22 cases (associated with HCV infection in 81%), Pneumocystis carinii pneumonia in 21, Cytomegalovirus (CMV) infection in 19, Mycobacterium avium-intracellulaire (MAI) infection in 17, bacterial pneumonia in 14, tuberculosis in 12, and lymphoma in 13 cases. Forty-six (30.6%) patients had at least one clinical diagnosis that was confirmed by autopsy, i.e., there was 40.6% agreement between pre- and postmortem findings. Forty-six (30.6%) patients had at least one clinical diagnosis that was not confirmed at autopsy, whereas 41 (27.3%) had at least one AIDS-related or unrelated disease that was not suspected clinically. The results obtained by limited autopsy are principally comparable to those achieved by full necropsy, with the advantages of decreasing the contagious risk, saving cost and time, including a rapid final diagnosis, and easily obtaining the consent for postmortem examination so that necropsy studies may be performedon a larger number of patients, thus contributing to a better understanding of the spectrum of HIV infection in our environment.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 05:20:14