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Titolo:
Value of combined Ga-67 and Tc-99(m)-human immunoglobulin G whole-body scanning in malignant lymphoma
Autore:
Kucuk, NO; Aras, G; Soylu, A; Ozcan, M; Ibis, E; Dincol, D;
Indirizzi:
Ankara Univ, Fac Med, Dept Nucl Med, TR-06100 Ankara, Turkey Ankara Univ Ankara Turkey TR-06100 ept Nucl Med, TR-06100 Ankara, Turkey
Titolo Testata:
NUCLEAR MEDICINE COMMUNICATIONS
fascicolo: 3, volume: 22, anno: 2001,
pagine: 325 - 329
SICI:
0143-3636(200103)22:3<325:VOCGAT>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
TREATED LYMPHOMA; HODGKINS-DISEASE; RESIDUAL MASS; SCINTIGRAPHY; MANAGEMENT; SPECT;
Keywords:
Ga-67; Tc-99(m)-HIG; malignant lymphoma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Kucuk, NO Ankara Univ, Fac Med, Dept Nucl Med, TR-06100 Ankara, Turkey Ankara Univ Ankara Turkey TR-06100 ed, TR-06100 Ankara, Turkey
Citazione:
N.O. Kucuk et al., "Value of combined Ga-67 and Tc-99(m)-human immunoglobulin G whole-body scanning in malignant lymphoma", NUCL MED C, 22(3), 2001, pp. 325-329

Abstract

Human immunoglobulin G labelled with Tc-99(m) (Tc-99(m)-HIG) is an agent introduced for the localization of inflammatory lesions. There is also a limited number of reports concerning the uptake of this agent by malignant lesions. The aim of this study was to evaluate the uptake of Tc-99(m)-HIG by lymphoma. Twenty-three patients (five female, 18 male) with known Hodgkin's or non-Hodgkin's lymphoma for a period of 2-6 pears (mean 4.2 years) and which, by using computed tomography (CT), showed recurrence, were included inthe study. The patients were aged between 32 and 68 years (mean 38 +/- 5 years). No evidence of inflammation or infection was seen in any of these patients. CT, Tc-99(m)-HIG and a Ga-67 scan were performed in the same week. CT showed abdominal involvement in 17 patients, pelvic involvement in 11, and thorax involvement in 11. 99Tcm-HIG showed higher sensitivity (94.1%) inthe abdomen, a similar sensitivity (63.6%) in thorax, but lower (18.1%) inpelvic area than for Ga-67. Tc-99(m)-HIG was found to be more useful for the evaluation of abdominal involvement compared to Ga-67 due to gastrointestinal excretion of the latter. The resolution of 67Ga was better than Tc-99(m)-HIG in thorax and pelvis. Using Tc-99(m)- HIG and Ga-67 together in lymphoma may increase sensitivity. ((C) 2001 Lippincott Williams & Wilkins).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 02:38:00