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Titolo:
First experiences in combination therapy using olanzapine with SSRIs (Citalopram, paroxetine) in delusional depression
Autore:
Konig, F; von Hippel, C; Petersdorff, T; Neuhoffer-Weiss, M; Wolfersdorf, M; Kaschka, WP;
Indirizzi:
Univ Ulm, Dept Psychiat 1, D-88214 Ravensburg, Germany Univ Ulm Ravensburg Germany D-88214 chiat 1, D-88214 Ravensburg, Germany Bezirkskrankenhaus Bayreuth, Bayreuth, Germany Bezirkskrankenhaus Bayreuth Bayreuth Germany ayreuth, Bayreuth, Germany
Titolo Testata:
NEUROPSYCHOBIOLOGY
fascicolo: 3, volume: 43, anno: 2001,
pagine: 170 - 174
SICI:
0302-282X(2001)43:3<170:FEICTU>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
PSYCHOTIC DEPRESSION; DRUG-INTERACTIONS; ANTIDEPRESSANT; SCHIZOPHRENIA; PERPHENAZINE; HALOPERIDOL; DISORDERS; EFFICACY; ZOTEPINE; TRIAL;
Keywords:
delusional depression; citalopram; paroxetine; olanzapine; combination therapy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Konig, F Univ Ulm, Dept Psychiat 1, Postfach 20 44, D-88214 Ravensburg, Germany Univ Ulm Postfach 20 44 Ravensburg Germany D-88214 burg, Germany
Citazione:
F. Konig et al., "First experiences in combination therapy using olanzapine with SSRIs (Citalopram, paroxetine) in delusional depression", NEUROPSYCHB, 43(3), 2001, pp. 170-174

Abstract

In an open prospective study, 26 patients with delusional depression (mood-congruent psychotic features: DSM-IV 296.4) were treated over 5 weeks witha combination of SSRI (citalopram, n = 22, or paroxetine, n = 4) and the neuroleptic olanzapine. The course of therapy was evaluated with the Hamilton depression scale (HAMD). Not only the total HAMD score, but also the subscores for affectivity and delusional symptoms decreased significantly. After the end of the 5-week combination therapy, 18 out of 26 patients (69%) could be discharged as responders to outpatient treatment. The course of treatment was characterized by excellent tolerance. Copyright (C) 2001 S. Karger AG. Basel.

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Documento generato il 25/01/20 alle ore 19:11:17