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Titolo:
Genes for left-handedness: How to search for the needle in the haystack?
Autore:
Van Agtmael, T; Forrest, SM; Williamson, R;
Indirizzi:
Murdoch Childrens Res Inst, RCH, Parkville, Vic 3052, Australia Murdoch Childrens Res Inst Parkville Vic Australia 3052 c 3052, Australia Univ Melbourne, Parkville, Vic 3052, Australia Univ Melbourne Parkville Vic Australia 3052 arkville, Vic 3052, Australia
Titolo Testata:
LATERALITY
fascicolo: 2, volume: 6, anno: 2001,
pagine: 149 - 164
SICI:
1357-650X(200104)6:2<149:GFLHTS>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
CYSTIC-FIBROSIS GENE; LEFT-RIGHT ASYMMETRY; LINKAGE ANALYSIS; HAND PREFERENCE; COMPLEX TRAITS; IDENTIFICATION; CLONING; SCHIZOPHRENIA; CHROMOSOME; DISSECTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: Van Agtmael, T Murdoch Childrens Res Inst, RCH, Flemington Rd, Parkville, Vic 3052, Australia Murdoch Childrens Res Inst Flemington Rd Parkville Vic Australia 3052
Citazione:
T. Van Agtmael et al., "Genes for left-handedness: How to search for the needle in the haystack?", LATERALITY, 6(2), 2001, pp. 149-164

Abstract

Although several genes that determine left-right asymmetry for structural syndromes such as situs inversus have been characterised in recent years (Supp, Witte, Potter, & Brueckner, 1997), there has been little progress in determining which genes or loci predispose to left-right handedness in humans. Linkage analysis has been used widely for the localisation of genes followed by their positional cloning. The complex genetics of handedness is oneof the greatest problems for standard linkage analysis. Several genetic models have been proposed for the inheritance of handedness in humans. On thebasis of these models, left-handedness can be considered a common single gene trait with a high gene frequency and a non-mendelian inheritance pattern. We report here a possible strategy, using these genetic models, that canbe applied for the identification for genes determining handedness in humans.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 11:54:04