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Titolo:
Intraoral distribution of Actinobacillus actinomycetemcomitans in young adults with minimal periodontal disease
Autore:
Muller, HP; Heinecke, A; Fuhrmann, A; Eger, T; Zoller, L;
Indirizzi:
Univ Heidelberg, Sch Dent Med, D-69120 Heidelberg, Germany Univ Heidelberg Heidelberg Germany D-69120 , D-69120 Heidelberg, Germany German Armed Forces Med Serv, Cent Inst, Koblenz, Germany German Armed Forces Med Serv Koblenz Germany ent Inst, Koblenz, Germany Univ Munster, Inst Med Informat & Biostat, D-4400 Munster, Germany Univ Munster Munster Germany D-4400 t & Biostat, D-4400 Munster, Germany German Armed Forces Cent Hosp, Koblenz, Germany German Armed Forces Cent Hosp Koblenz Germany nt Hosp, Koblenz, Germany
Titolo Testata:
JOURNAL OF PERIODONTAL RESEARCH
fascicolo: 2, volume: 36, anno: 2001,
pagine: 114 - 123
SICI:
0022-3484(200104)36:2<114:IDOAAI>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
LOCALIZED JUVENILE PERIODONTITIS; LONGITUDINAL DATA-ANALYSIS; EARLY-ONSET PERIODONTITIS; PORPHYROMONAS-GINGIVALIS; SUBGINGIVAL PLAQUE; EXTRACREVICULAR LOCATIONS; SUPRAGINGIVAL PLAQUE; EIKENELLA-CORRODENS; LEUKOTOXIN; PERICORONITIS;
Keywords:
Actinobacillus actinomycelemcomitans; microbial ecology; ore-pharyngeal cavity; periodontal health;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
56
Recensione:
Indirizzi per estratti:
Indirizzo: Muller, HP Univ Heidelberg, Sch Dent Med, Neuenheimer Feld 400, D-69120 Heidelberg, Germany Univ Heidelberg Neuenheimer Feld 400 Heidelberg Germany D-69120
Citazione:
H.P. Muller et al., "Intraoral distribution of Actinobacillus actinomycetemcomitans in young adults with minimal periodontal disease", J PERIOD RE, 36(2), 2001, pp. 114-123

Abstract

The aim of the present study was to investigate the intraoral distributionof Actinobacillus actinomycetemcomitans in young adults with minor signs of periodontal disease but harboring the organisms in the oral cavity. 17 healthy volunteers, 20 to 27 years of age, participated, Samples from mucosalsurfaces of the ore-pharyngeal cavity and saliva (n= 221) as well as subgingival plaque from every tooth in (n= 477) were selectively cultivated for A. actinomycetemcomitans c . Species identity and presence of the leukotoxcin encoding gene, ltxA, were checked by multiplex polymerase chain reaction. Moreover, the leukotoxin promoter region was analyzed. No isolate harbored a 530 bp deletion in the promoter region of the leukotoxin gene, signaling minimally toxic strains. 42.1 +/- 30.4%, extracrevicular and 34.4 +/- 29.5% subgingival samples were culture-positive. In extracrevicular samples. the organism could easily be recovered from check mucosa (62%), saliva (59%)and the palatal tonsils (41%). Mean log-transformed numbers of A. actinomycetemcomitans colony forming units (CFU/ml) in culture-positive material ranged between 1.8 from the hard palate and 2.3 from 10 mul saliva. The highest prevalence in subgingival plaque was observed at maxillary 3rd molars (55%) followed by maxillary lateral incisors (50%) and mandibular 3rd molars (41%). Mean log-transformed counts of CFU/ml ranged between 2.2 at maxillary 3rd molars and 3.4 at upper central incisors. When adjusted for jaw, siteand tooth type, the odds of isolating higher numbers of the organism were increased with every mm probing depth by a factor of 1.35 (p < 0.05). The odds ratio for bleeding on probing was 1.38. Thus, in this young adult population with minor periodontal disease, A. actinomycetemcomitans was mainly associated with some deviation from gingival health. Of concern might be a miniority of subjects (29%) with an extremely wide distribution of the organism in the oral cavity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 01:13:10