Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
The immune response of thymic cells from the turtle Mauremys caspica
Autore:
Munoz, FJ; De la Fuente, M;
Indirizzi:
Univ Complutense Madrid, Fac Ciencias Biol, Dept Fisiol Anim, Madrid 28040, Spain Univ Complutense Madrid Madrid Spain 28040 iol Anim, Madrid 28040, Spain Pompeu Fabra Univ Barcelona, Fac Hlth & Life Sci, Dept Expt & Hlth Sci, Barcelona, Spain Pompeu Fabra Univ Barcelona Barcelona Spain Hlth Sci, Barcelona, Spain
Titolo Testata:
JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTALPHYSIOLOGY
fascicolo: 3, volume: 171, anno: 2001,
pagine: 195 - 200
SICI:
0174-1578(200104)171:3<195:TIROTC>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
SNAKE PSAMMOPHIS-SIBILANS; NATURAL-KILLER-CELLS; SEASONAL-VARIATIONS; CHALCIDES-OCELLATUS; LYMPHOID-TISSUE; CYCLIC CHANGES; ANTIBODY; CYTOTOXICITY; LYMPHOCYTES; STIMULATION;
Keywords:
chemotaxis; cytotoxicity; mitogen; thymic cell; turtle;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
51
Recensione:
Indirizzi per estratti:
Indirizzo: De la Fuente, M Univ Complutense Madrid, Fac Ciencias Biol, Dept Fisiol Anim, Madrid 28040, Spain Univ Complutense Madrid Madrid Spain 28040 28040, Spain
Citazione:
F.J. Munoz e M. De la Fuente, "The immune response of thymic cells from the turtle Mauremys caspica", J COMP PH B, 171(3), 2001, pp. 195-200

Abstract

In the present work several known mammalian leukocyte functions such as directed mobility, proliferative response to mitogens, antibody-dependent cellular cytotoxicity (ADCC) and natural killer (NK)-mediated cytotoxicity were studied in female and male Mauremys caspica turtles. Since the reptilian thymus shows seasonal variations in its structure, we have Performed all the assays along the seasonal cycle. Our results show that thymic cells from M. caspica are able to migrate through a chemo-attractant gradient, to proliferate in response to the mitogens phytohaemagglutinin (PHA) and concanavalin A (Con A), and to kill tumoral target cells by both ADCC-mediated and NK-mediated cytotoxicity. Those functions were differentially affected by the seasonal cycle; in general, in autumn the functions studied showed the smallest values for both sexes, while in summer the highest values of cytotoxicity and chemotaxis were found in females. The proliferative responses to PHA and Con A were higher for both sexes in spring and for females in winter than in the other seasons. In summary, thymic cells from M. caspica show a wide range of immune functions, and these are modulated heterogeneously by the seasonal cycle in both sexes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 11:14:56