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Titolo:
What to think of "adjuvant" or "neoadjuvant" thermotherapy in the treatment of uveal melanomas?
Autore:
Grange, JD;
Indirizzi:
Clin Ophtalmol Univ, Hop Croix Rousse, F-69004 Lyon, France Clin OphtalmolUniv Lyon France F-69004 oix Rousse, F-69004 Lyon, France
Titolo Testata:
JOURNAL FRANCAIS D OPHTALMOLOGIE
fascicolo: 2, volume: 24, anno: 2001,
pagine: 191 - 198
SICI:
0181-5512(200102)24:2<191:WTTO"O>2.0.ZU;2-F
Fonte:
ISI
Lingua:
FRE
Soggetto:
TRANSPUPILLARY THERMOTHERAPY; CHOROIDAL MELANOMA; MALIGNANT-MELANOMA; HYPERTHERMIA; THERMORADIOTHERAPY; MANAGEMENT; RADIATION;
Keywords:
transpupillary thermotherapy; 810Nm diode laser; choroidal melanoma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Grange, JD Clin Ophtalmol Univ, Hop Croix Rousse, 103 Grande Rue, F-69004 Lyon, France Clin Ophtalmol Univ 103 Grande Rue Lyon France F-69004 France
Citazione:
J.D. Grange, "What to think of "adjuvant" or "neoadjuvant" thermotherapy in the treatment of uveal melanomas?", J FR OPHTAL, 24(2), 2001, pp. 191-198

Abstract

Before 810Nm laser thermotherapy has been used for uveal melanoma, severalauthors especially in Essen (Germany) were asking themselves about the possibilities of xenon are or argon laser effects on uveal melanomas. High rates of recurrences due to the non penetration of therapeutic light till the sclera had led to the conception of using adjuvant thermotherapy associatedwith radiotherapy, through microwaves, ultrasounds or ferromagnetic seeds. In Leyden (Netherlands) was proposed the use of 810Nm laser diode initially as an adjuvant to radiotherapy and later on as primary isolated treatment("neo adjuvant" TTT), especially for small tumours located in the posterior pole (juxta-papillary tumours). TTT used alone should not be proposed fortumours of inital height of more than 3,5 to 4mm. "Neo adjuvant" thermotherapy finds some other indications like decompensated naevi responsible for macular detachment. Bigger peripheral tumours stabilized by protonbeam therapy but associated with persistent detachment after the 12th month could betreated with "adjuvant" TTT. Finally the importance of the quality of the tumour edges treatment should be emphasized.

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Documento generato il 04/12/20 alle ore 21:57:23