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Titolo:
Novel method for assessing myocardial perfusion - Visualization and measurement of intramyocardial coronary blood flow in the entire left ventricularwall using contrast enhanced, high frequency Doppler echocardiography
Autore:
Ujino, K; Teragaki, M; Ota, T; Muro, T; Watanabe, H; Yoshiyama, M; Takeuchi, K; Yoshikawa, J;
Indirizzi:
Osaka City Univ, Sch Med, Dept Internal Med 1, Abeno Ku, Osaka 5458585, Japan Osaka City Univ Osaka Japan 5458585 ed 1, Abeno Ku, Osaka 5458585, Japan
Titolo Testata:
JAPANESE HEART JOURNAL
fascicolo: 1, volume: 42, anno: 2001,
pagine: 101 - 113
SICI:
0021-4868(200101)42:1<101:NMFAMP>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTRAVENOUS PERIPHERAL INJECTION; TRANSESOPHAGEAL COLOR DOPPLER; NONINVASIVE ASSESSMENT; TRANSTHORACIC ECHOCARDIOGRAPHY; 2-DIMENSIONAL ECHOCARDIOGRAPHY; VELOCITY DYNAMICS; ARTERY STENOSIS; ANATOMY; RESERVE; AGENT;
Keywords:
intramyocardial coronary blood flow; spectral Doppler; intravenous contrast injection;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Ujino, K Osaka City Univ, Sch Med, Dept Internal Med 1, Abeno Ku, 1-4-3 Asahi Machi, Osaka 5458585, Japan Osaka City Univ 1-4-3 Asahi Machi Osaka Japan 5458585 585, Japan
Citazione:
K. Ujino et al., "Novel method for assessing myocardial perfusion - Visualization and measurement of intramyocardial coronary blood flow in the entire left ventricularwall using contrast enhanced, high frequency Doppler echocardiography", JPN HEART J, 42(1), 2001, pp. 101-113

Abstract

Using a high frequency ultrasonic transducer, intramyocardial coronary blood flow (IM-CBF) can be visualized and evaluated during hemodynamic changesin the anterior wall and septum of the left ventricle (LW). We tested the hypothesis that detection and quantitative measurement of IM-CBF of entire LV segments are feasible using a high frequency ultrasonic transducer in conjunction with intravenous contrast injection in vivo. A 3 - 8 MHz transducer was used to image and measure IM-CBF in 10 anesthetized dogs. We obtained a color Doppler image of IM-CBF in the LV short-axisview after intravenous Levovist(TM) injection (25 mg/ml). The IM-CBF velocity was recorded using spectral Doppler in the antero-septal and infero-posterior wall of closed chest dogs and in the entire LV after opening the chest. A significant increase in IM-CBF velocity was observed in all LV regions after adenosine 5 '- triphosphate (ATP) administration. After Levovist(TM) injection, the visualization of IM-CBF was improved and the spectral Doppler pattern of coronary flow velocity was clarified compared to baseline. IM-CBF was assessed in the antero-septal region of the LV before and after left anterior descending coronary artery occlusion. A high frequency ultrasonic transducer in conjunction with intravenous contrast injection improved IM-CBF visualization, enabling quantitative evaluation of the intramyocardial coronary circulation in the entire LV after coronary occlusion and hyperemia. This study may represent a step towards noninvasive assessment of myocardial perfusion before and after coronary reperfusion.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 20:08:41