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Titolo:
PAProC: a prediction algorithm for proteasomal cleavages available on the WWW
Autore:
Nussbaum, AK; Kuttler, C; Hadeler, KP; Rammensee, HG; Schild, H;
Indirizzi:
Univ Tubingen, Interfak Inst Zellbiol, Immunol Abt, D-72076 Tubingen, Germany Univ Tubingen Tubingen Germany D-72076 ol Abt, D-72076 Tubingen, Germany
Titolo Testata:
IMMUNOGENETICS
fascicolo: 2, volume: 53, anno: 2001,
pagine: 87 - 94
SICI:
0093-7711(200103)53:2<87:PAPAFP>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
MHC CLASS-I; EPSTEIN-BARR-VIRUS; DISTINCT PROTEOLYTIC PROCESSES; GLY-ALA REPEAT; PROTEIN AGGREGATION; NUCLEAR ANTIGEN-1; PEPTIDE; DEGRADATION; INHIBITION; EPITOPE;
Keywords:
proteasome; cleavage prediction; algorithm; MHC; CTL epitope;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Schild, H Univ Tubingen, Interfak Inst Zellbiol, Immunol Abt, Morgenstelle15, D-72076 Tubingen, Germany Univ Tubingen Morgenstelle 15 Tubingen Germany D-72076 Germany
Citazione:
A.K. Nussbaum et al., "PAProC: a prediction algorithm for proteasomal cleavages available on the WWW", IMMUNOGENET, 53(2), 2001, pp. 87-94

Abstract

The first version of PAProC (Prediction Algorithm for Proteasomal Cleavages) is now available to the general public. PAProC is a prediction tool for cleavages by human and yeast proteasomes, based on experimental cleavage data. It will be particularly useful for immunologists working on antigen processing and the prediction of major histocompatibility complex class I molecule (MHC I) ligands and cytotoxic T-lymphocyte (CTL) epitopes. Likewise, in cases in which proteasomal protein degradation has been indicated in disease, PAProC can be used to assess the general cleavability of disease-linked proteins. On its web site (http://www.paproc.de), background information and hyperlinks are provided for the user (e.g., to SYFPEITHI, the database for the prediction of MHC I ligands).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/10/20 alle ore 09:42:13