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Titolo:
The relationship between early renal status, and the resolution of vesico-ureteric reflux and bladder function at 16 months
Autore:
Godley, ML; Desai, D; Yeung, CK; Dhillon, HK; Duffy, PG; Ransley, PG;
Indirizzi:
Inst Child Hlth, London WC1N 1EH, England Inst Child Hlth London EnglandWC1N 1EH d Hlth, London WC1N 1EH, England Great Ormond St Hosp Children NHS Trust, London WC1N 3JH, England Great Ormond St Hosp Children NHS Trust London England WC1N 3JH England Chinese Univ Hong Kong, Prince Wales Hosp, Dept Surg, Sha Tin 100083, HongKong Chinese Univ Hong Kong Sha Tin Hong Kong 100083 Sha Tin 100083, HongKong
Titolo Testata:
BJU INTERNATIONAL
fascicolo: 6, volume: 87, anno: 2001,
pagine: 457 - 462
SICI:
1464-4096(200104)87:6<457:TRBERS>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRIMARY VESICOURETERAL REFLUX; URINARY-TRACT INFECTION; GROSS BILATERAL REFLUX; DETRUSOR HYPERCONTRACTILITY; INFANTS; OBSTRUCTION; NEPHROPATHY; CHILDREN; KIDNEY;
Keywords:
vesico-ureteric reflux; kidney disease; urodynamics; paediatrics;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Godley, ML Inst Child Hlth, 30 Guilford St, London WC1N 1EH, England Inst Child Hlth 30 Guilford St London England WC1N 1EH England
Citazione:
M.L. Godley et al., "The relationship between early renal status, and the resolution of vesico-ureteric reflux and bladder function at 16 months", BJU INT, 87(6), 2001, pp. 457-462

Abstract

Objective To examine, in infants presenting with vesicoureteric reflux (VUR). the relationship between the presence of initial renal abnormalities with the outcome of VUR and bladder function at 16 months of age. Patients and methods The study group comprised 40 infants (32 boys) presenting consecutively (29 after prenatal detection) with VUR grade III or greater (bilateral in 29) on the initial micturating cystogram (median age 8 weeks). The initial presence of abnormal kidneys was determined from isotopicrenography and/or ultrasonography. These data were correlated with the outcome of VUR, from direct isotope cystography, and bladder function assessedby natural filling urodynamics, examined at age 16 months (mean 16.4 months, SD 2.1). Results Three groups were identified. Group 1 (eight boys and six girls) had normal kidneys bilaterally; initially grade III VUR was common, At 16 months bladder function was normal in 10 children and none had VUR (complete resolution). Group 2 (14 boys and two girls) had unilateral renal abnormalities; initially VUR was predominantly grade IV or grade V. At 16 months bladder function was normal in eight children and VUR resolved in eight, five of these with normal bladder function. Group 3 (10 boys) had bilateral renal abnormalities. Initially grade V VUR predominated: at 16 months the bladder function was normal in only one, and in the rest the emptying dynamics were abnormal. All 10 boys had persisting VUR (no resolution). Conclusions In infants with moderate or severe VUR, resolution at 16 months old is associated with normal kidneys in a similar proportion of boys andgirls. Resolution also correlates well with normal bladder function. Presentation in infancy with bilateral abnormal kidneys, associated with severe VUR in boys, is a poor prognostic sign for the early outcome of VUR and forbladder function.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 09:19:52