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Titolo:
Experimental study on facial nerve regeneration with or without geniculateganglionectomy
Autore:
Wang, ZM; Dai, CF; Zhang, YH;
Indirizzi:
Shanghai Med Univ, Dept Otolaryngol, Eye Ear Nose & Throat Hosp, Shanghai 200031, Peoples R China Shanghai Med Univ Shanghai Peoples R China 20003100031, Peoples R China
Titolo Testata:
ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
fascicolo: 4, volume: 127, anno: 2001,
pagine: 422 - 425
SICI:
0886-4470(200104)127:4<422:ESOFNR>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
SURGICAL-MANAGEMENT; NEURALGIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Dai, CF Shanghai Med Univ, Dept Otolaryngol, Eye Ear Nose & Throat Hosp, Shanghai 200031, Peoples R China Shanghai Med Univ Shanghai Peoples R China 200031 eoples R China
Citazione:
Z.M. Wang et al., "Experimental study on facial nerve regeneration with or without geniculateganglionectomy", ARCH OTOLAR, 127(4), 2001, pp. 422-425

Abstract

Objective: To investigate regeneration of the distal facial nerve following nerve grafting within the tympanic segment with geniculate ganglion preservation or dissection. Design: Randomized controlled trial. Subjects: Twenty-three adult New Zealand albino rabbits were used in this study. Interventions: A 2-mm tympanic segment of the facial nerve was removed, and the greater auricular nerve was harvested for grafting in all animals. Ingroup 1 (10 rabbits), the geniculate ganglion was preserved. In group 2 (13 rabbits), the geniculate ganglion was dissected. Mastoidal and extratemporal segments of the facial nerve were harvested 3 months postoperatively for histological examination by electron microscopy. Results: The number of myelinated axons in normal facial nerves was 1819.6+/- 535.6. In group 1, the number of myelinated axons was 123.6 +/- 31.1, and, compared with normal facial nerves, the diameter of the regenerative axons was decreased and the sheath thickness in the regenerative fiber was diminished. In group 2, the number of myelinated axons was 515.1 +/- 103.1, while the myelin sheath thickness was proportionate to axon diameter. (Dataare given as mean +/- SD. )Conclusion: Geniculate ganglionectomy may improve motor axon regeneration.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 07:13:34