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Titolo:
Tramadol for postoperative shivering: A double-blind comparison with pethidine
Autore:
Bhatnagar, S; Saxena, A; Kannan, TR; Punj, J; Panigrahi, M; Mishra, S;
Indirizzi:
All India Inst Med Sci, Inst Rotary Canc Hosp, Unit Anesthesiol, New Delhi, India All India Inst Med Sci New Delhi India it Anesthesiol, New Delhi, India
Titolo Testata:
ANAESTHESIA AND INTENSIVE CARE
fascicolo: 2, volume: 29, anno: 2001,
pagine: 149 - 154
SICI:
0310-057X(200104)29:2<149:TFPSAD>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
MEPERIDINE; PLACEBO; ANESTHESIA; CLONIDINE; DOXAPRAM;
Keywords:
complications : shivering; postoperative; analgesics opioids : pethidine, tramadol;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Bhatnagar, S No 2,North Ave,IIT Campus, New Delhi 110016, India No 2,North Ave,IIT Campus New Delhi India 110016 016, India
Citazione:
S. Bhatnagar et al., "Tramadol for postoperative shivering: A double-blind comparison with pethidine", ANAESTH I C, 29(2), 2001, pp. 149-154

Abstract

In most operating and recovery rooms, shivering is controlled by the use of humidifiers, warming blankets, and inhalation of humidified heated oxygen. However, pharmacological control is an effective alternate treatment modality. This randomized, double-blind trial conducted in 30 ASA Grade 1 or 2 patients, was designed to explore the efficacy of tramadol and pethidine inthe treatment of post-anaesthetic shivering,Tramadol is an inhibitor of the re-uptake of serotonin (5-hydroxyptamine) and norepinephrine in the spinal cord. This facilitates 5-hydroxytryptaminerelease, which influences thermoregulatory control. We compared the efficacy of tramadol with that of pethidine, presently a widely used drug for thecontrol of shivering. Patients received either tramadol 1 mg/kg or pethidine 0.5 mg/kg intravenously and the grade of shivering, pulse rate, blood pressure and respiratory rate were observed every 10 minutes after injection for one hour. Shivering was significantly more likely to have ceased in thetramadol group (12 of 15 versus 4 of 15 cases. P<0.05) at 10 minutes afterdrug administration and this control was better sustained. No patients receiving tramadol had a recurrence of shivering. It is concluded that intravenous tramadol 1 mg/kg is more effective for die treatment of postoperative shivering than pethidine 0.5 mg/kg.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 04:17:42