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Titolo:
Vesico-ureteric reflux in adults with neuropathic bladders treated with Polydimethylsiloxane (Macroplastique((R)))
Autore:
Shah, N; Kaibr, MJ; Lane, T; Avenell, S; Shah, PJR;
Indirizzi:
Royal Natl Orthopaed Hosp, Spinal Injuries Unit, Stanmore HA7 4LP, Middx, England Royal Natl Orthopaed Hosp Stanmore Middx England HA7 4LP , Middx, England Inst Urol & Nephrol, London, England Inst Urol & Nephrol London EnglandInst Urol & Nephrol, London, England
Titolo Testata:
SPINAL CORD
fascicolo: 2, volume: 39, anno: 2001,
pagine: 92 - 96
SICI:
1362-4393(200102)39:2<92:VRIAWN>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
VESICOURETERAL REFLUX; ENDOSCOPIC TREATMENT; TEFLON-INJECTION; MICROIMPLANTS; IMPLANTATION; INCONTINENCE; EXPERIENCE;
Keywords:
vesico-uretic reflux; endoscopic injection; Macroplastique((R)); neuropathic bladder;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Shah, N Royal Natl Orthopaed Hosp, Spinal Injuries Unit, Brockley Hill, Stanmore HA7 4LP, Middx, England Royal Natl Orthopaed Hosp Brockley Hill Stanmore Middx England HA7 4LP
Citazione:
N. Shah et al., "Vesico-ureteric reflux in adults with neuropathic bladders treated with Polydimethylsiloxane (Macroplastique((R)))", SPINAL CORD, 39(2), 2001, pp. 92-96

Abstract

Objective: To establish the efficacy of Macroplastique (R) in treating vesico-ureteric reflux (VUR) in adults with neuropathic bladder dysfunction,Patients and methods: Fifteen patients (12 male and three female), age range 19 to 80 years (mean age 38) were included in this study. Diagnosis was confirmed by videourodynamics. In seven patients reflux was present bilaterally. Twenty-two refluxing ureters were treated. Twelve patients had detrusor hyper-reflexia, two had areflexic bladders and one had loss of bladder wall compliance. According to the International Grading System, 10 ureters had grade IV reflux, five had grade III reflux, five had grade II reflux, and two had grade I rc flux. Macroplastique (R) (0.5-1.5 ml) was injected submucosally under each ureteric orifice to convert the opening to a slit likeshape. The patients were followed up from 9 to 68 months,Results: VUR was completely resolved in 72.7% (16) ureters following a single injection and in a further 4.5% (1) ureter following a second injection. 9.1% (2) ureters were improved and treatment failed in 13.7% (3) ureters. Two patients showed a recurrence of reflux and 4 years after primary injection and subsequently had a curative second injection, Most of the patientsin whom VUR was cured or improved showed a reduction in laboratory proven urinary infection rates. Conclusion: Macroplastique (R) produced an excellent result (86% with complete resolution or improvement of reflux) in treating VUR in adult neuropathic bladders. This is comparable to larger studies carried out on the paediatric population, This is an easy procedure, which avoids major surgery andcan be performed as a day case. In cases of failure or recurrence, repeat injection or open surgery can be undertaken without any added complications.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 03:08:30