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Titolo:
Evaluation of left ventricular myocardial function in patients with coronary artery disease and myocardial dysfunction before and after coronary artery bypass grafting by Cine Magnetic Resonance Imaging
Autore:
Juergens, KU; Wichter, T; Renger, B; Bruns, HJ; Reimer, P; Tombach, B; Vahlhaus, C; Janssen, FW; Breithardt, G; Heindel, W;
Indirizzi:
Univ Klinikum Munster, Inst Klin Radiol, Munster, Germany Univ Klinikum Munster Munster Germany nst Klin Radiol, Munster, Germany Univ Klinikum Munster, Med Klin & Poliklin, Munster, Germany Univ KlinikumMunster Munster Germany Klin & Poliklin, Munster, Germany
Titolo Testata:
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN
fascicolo: 3, volume: 173, anno: 2001,
pagine: 211 - 217
SICI:
1438-9029(200103)173:3<211:EOLVMF>2.0.ZU;2-R
Fonte:
ISI
Lingua:
GER
Soggetto:
CARDIAC-FUNCTION; REVASCULARIZATION; REPRODUCIBILITY; SURVIVAL; EXERCISE; HEART; MASS;
Keywords:
cardiac MRI; coronary artery disease; myocardial function; chronic ischemic myocardium; hibernation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Juergens, KU Univ Munster, Interdisziplinares Zentrum, Klin Forsch IZKF Munster, Inst Klin Radiol, Albert Schweitzer Str 33, D-48129 Munster, GermanyUniv Munster Albert Schweitzer Str 33 Munster Germany D-48129
Citazione:
K.U. Juergens et al., "Evaluation of left ventricular myocardial function in patients with coronary artery disease and myocardial dysfunction before and after coronary artery bypass grafting by Cine Magnetic Resonance Imaging", ROFO-F RONT, 173(3), 2001, pp. 211-217

Abstract

Purpose: To evaluate left Ventricular (LV) myocardial function in ten patients with coronary artery disease (CAD) preoperatively and 6 months after coronary bypass grafting (CABG) by cardiac MRI. Material and methods: Ten patients (mean 65.2 +/- 5.9 years) with angiographically proven CAD and an indication for elective CABG underwent prospective evaluation of global LV function and regional walt motion by Cine-MRI at rest using a multiphase FLASH-2D sequence following regions of interest (ROI)-defined diagnostics of regional myocardial wall motion by means of le-Vocardiography. Within the ROIs a total of 613 LV myocardial segments were analyzed preceding and following surgical revascularization. Results were compared with the data of 10 healthy volunteers. Results: Preoperatively, patients showed reduced stroke Volume and ejection fraction compared with volunteers (p < 0.01). Enddiastolic wall thickness (EDWT) and systolic wall thickening (SWT) were significantly lower in the patients (p < 0.01). Based on preoperative levocardiography ROI-defined myocardial segments showed a significantly lower preoperativeEDWT in areas with wall motion abnormalities (7.4 +/- 2.5 mm; p < 0.01) than in normal myocardium (9.2 <plus/minus> 2.1 mm). Ejection fraction (p < 0.05), endsystolic wall thickness, and SWT (p < 0.01) improved significantlyafter bypass surgery. On ROI-defined analysis myocardial segments with impaired preoperative wall motion (n = 243) showed a significant increase of EDWT, ESWT and SWT (p(0.01). Conclusion: In patients with CAD, cardiac MRI enables the non-invasive determination of postinfarctional LV remodeling with an increased EDWT of myocardial segments with normal regional wall motionand of the improvement in global and regional myocardial function following coronary bypass surgery.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 12:18:12