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Titolo:
Perfusion MR imaging of the heart with TrueFISP.
Autore:
Schreiber, WG; Schmitt, M; Kalden, P; Horstick, G; Gumbrich, T; Petersen, S; Mohrs, O; Kreitner, KF; Voigtlander, T; Thelen, M;
Indirizzi:
Univ Mainz, Klin & Poliklin Radiol, D-55131 Mainz, Germany Univ Mainz Mainz Germany D-55131 Poliklin Radiol, D-55131 Mainz, Germany Univ Mainz, Med Klin, D-55131 Mainz, Germany Univ Mainz Mainz Germany D-55131 Mainz, Med Klin, D-55131 Mainz, Germany
Titolo Testata:
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN
fascicolo: 3, volume: 173, anno: 2001,
pagine: 205 - 210
SICI:
1438-9029(200103)173:3<205:PMIOTH>2.0.ZU;2-W
Fonte:
ISI
Lingua:
GER
Soggetto:
MYOCARDIAL PERFUSION; PASS;
Keywords:
perfusion; myocardium; Magnetic Resonance Imaging; TrueFISP; ultrafast imaging;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Schreiber, WG Univ Mainz, Radiol Klin, Langenbeckstr 1, D-55131 Mainz, Germany Univ Mainz Langenbeckstr 1 Mainz Germany D-55131 z, Germany
Citazione:
W.G. Schreiber et al., "Perfusion MR imaging of the heart with TrueFISP.", ROFO-F RONT, 173(3), 2001, pp. 205-210

Abstract

Objective: Development and test of a saturation-recovery TrueFISP (SR-Trufi) pulse sequence for myocardial perfusion MR imaging (MRI) using improved gradient hardware. Material and Methods: Measurements were performed on a 1.5T scanner with prototype gradients (50 mT/m, minimum rise time 300 mus. T,weighted first-pass MRI of Gd-DTPA (0.025 mu mol/kg) kinetics in the myocardium was performed using an SR-Trufi pulse sequence (T-R/T-E/alpha = 2.6 ms/1.4 ms/55 degrees) with a saturation preparation of TD = 30ms before the TrueFISP readout. Measurements were performed in volunteers (n = 4) and in a pig model of chronic ischemia (n = 1) Results: In phantoms, the signal intensity was linear with contrast concentration up to 0.9 mmol/l kg Gd-DTPA. MR images obtained with SR-Trufi had a good image quality and high spatialresolution of 2.1 mm x 2.1 mm. Differences of the contrast agent's kinetics between a subendocardial perfusion deficit and neighboring myocardium were well visible on both MR images and signal-time curves derived from the region-of-interest analysis. Conclusion: SR-Trufi appears to be an interesting new technique for the assessment of myocardial microcirculation using dedicated cardiovascular MR systems.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/02/20 alle ore 17:22:59