Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Stimulant therapy and seizure risk in children with ADHD
Autore:
Hemmer, SA; Pasternak, JF; Zecker, SG; Trommer, BL;
Indirizzi:
Evanston Hosp, Div Neurol, Dept Pediat, Evanston, IL 60201 USA Evanston Hosp Evanston IL USA 60201 , Dept Pediat, Evanston, IL 60201 USA Northwestern Univ, Sch Med, Chicago, IL 60611 USA Northwestern Univ Chicago IL USA 60611 iv, Sch Med, Chicago, IL 60611 USA Northwestern Univ, Program Learning Disabil, Evanston, IL 60201 USA Northwestern Univ Evanston IL USA 60201 g Disabil, Evanston, IL 60201 USA
Titolo Testata:
PEDIATRIC NEUROLOGY
fascicolo: 2, volume: 24, anno: 2001,
pagine: 99 - 102
SICI:
0887-8994(200102)24:2<99:STASRI>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
FOLLOW-UP; METHYLPHENIDATE; DISORDER;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Trommer, BL Evanston Hosp, Div Neurol, Dept Pediat, 2650 Ridge Ave, Evanston, IL 60201USA Evanston Hosp 2650 Ridge Ave Evanston IL USA 60201 IL 60201USA
Citazione:
S.A. Hemmer et al., "Stimulant therapy and seizure risk in children with ADHD", PED NEUROL, 24(2), 2001, pp. 99-102

Abstract

Stimulants are an effective treatment frequently prescribed for attention-deficit-hyperactivity disorder (ADHD), but they commonly are believed to lower the threshold for seizures. Although several studies have revealed thatstimulants do not exacerbate well-controlled epilepsy, there is a paucity of data about seizure risk in nonepileptic children treated with stimulants. Two hundred thirty-four children (179 males, 9.1 +/- 3.6 years of age; 55females, 9.6 +/- 3.9 years of age) with uncomplicated ADHD received electroencephalograms (EEGs) performed in our institution. Thirty-six patients (15.4%) demonstrated epileptiform abnormalities, and 198 (84.6%) demonstratednormal or nonepileptiform EEGs, Rolandic spikes accounted for 40% of the abnormal EEGs and 60% of those with focal abnormalities, Stimulant therapy was elected by 205 of 234 patients (87.6%). Seizures occurred only in the treated group, in one of 175 patients with a normal EEG (incidence 0.6%, 95% confidence intervals 0%-1.7%) and three of 30 treated patients with epileptiform EEGs (incidence 10%, 95% confidence interval 0%-20.7%). Seizures occurred in two of 12 children (16.7 %) with rolandic spikes. These data suggest that a normal EEG can be used to assign children with ADHD to a category of minimal risk for seizure. In contrast, an epileptiform EEG in neurologically normal children with ADHD predicts considerable risk for the eventual occurrence of seizure. The risk, however, is not necessarily attributable to stimulant use, (C) 2001 by Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 00:24:32