Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Meningeal hemangiopericytoma: A retrospective study of 21 patients with special review of postoperative external radiotherapy
Autore:
Dufour, H; Metellus, P; Fuentes, S; Murracciole, X; Regis, J; Figarella-Branger, D; Grisoli, F;
Indirizzi:
Hop Timone Adultes, Serv Neurochirurg, Dept Neurosurg, F-13385 Marseille 5, France Hop Timone Adultes Marseille France 5 osurg, F-13385 Marseille 5, France Hop Timone Adultes, Dept Radiotherapy, F-13385 Marseille, France Hop Timone Adultes Marseille France F-13385 y, F-13385 Marseille, France Hop Timone Adultes, Dept Neuroradiosurg, F-13385 Marseille 5, France Hop Timone Adultes Marseille France 5 osurg, F-13385 Marseille 5, France Hop Timone Adultes, Dept Neuropathol, F-13385 Marseille 5, France Hop Timone Adultes Marseille France 5 athol, F-13385 Marseille 5, France
Titolo Testata:
NEUROSURGERY
fascicolo: 4, volume: 48, anno: 2001,
pagine: 756 - 763
SICI:
0148-396X(200104)48:4<756:MHARSO>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPINAL-CORD; MANAGEMENT; MENINGIOMA; EXPERIENCE;
Keywords:
angioblastic meningioma; brain neoplasm; gamma knife radiosurgery; meningeal hemangiopericytoma; meningeal neoplasm;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Dufour, H Hop Timone Adultes, Serv Neurochirurg, Dept Neurosurg, Rue St Pierre, F-13385 Marseille 5, France Hop Timone Adultes Rue St Pierre Marseille France 5 e 5, France
Citazione:
H. Dufour et al., "Meningeal hemangiopericytoma: A retrospective study of 21 patients with special review of postoperative external radiotherapy", NEUROSURGER, 48(4), 2001, pp. 756-763

Abstract

OBJECTIVE: To specify that postoperative radiotherapy is useful for preventing local recurrence and neuraxis recurrence of surgically treated meningeal hemangiopericytomas. METHODS: We retrospectively studied 21 patients with meningeal hemangiopericytoma who were followed in our department during a 34-year period. In 17 patients, the meningeal hemangiopericytoma was intracranial, and in 4 therewas an intradural extramedullary localization. These groups were studied separately. RESULTS: Of the 17 patients with intracranial hemangiopericytoma, all underwent surgery; 8 also underwent radiotherapy (5000-6400 rads) (Group I), and 9 did not (Group II). The mortality rate was zero for Group patients and 55% for Group II. The mean local recurrence rate was 52% (12.5% in Group I and 88% in Group II; P < 0.05). Neuraxis recurrences occurred in two patients in Group II, and none occurred in Group I (P = 0.4). Peripheral metastasis took place in two patients (22%) in Group II and in one patient (12.5%) in Group I (P = 0.5). Of the four patients with intradural extramedullary hemangiopericytoma, all underwent surgery. Two patients received 4000 rads of radiotherapy after intervention. No patient in this group had a recurrence. CONCLUSION: For patients with intracranial meningeal hemangiopericytoma, surgical removal followed by external radiotherapy reduced the risk of localrecurrence. It was not demonstrated that postoperative radiotherapy protected against neuraxis metastasis. Radiotherapy did not protect against peripheral metastasis, which can occur up to several years after the first operation. It appears that radiotherapy after surgery for local or neuraxis recurrence did not avoid further recurrence. Radiosurgery is indicated for recurrent tumors measuring less than 25 mm in greatest diameter. For intraduralextramedullary localizations, the value of postoperative radiotherapy is more questionable.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 19:11:26