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Titolo:
Immunohistochemical demonstration of L-serine distribution in the rat brain
Autore:
Yasuda, E; Ma, N; Semba, R;
Indirizzi:
Mie Univ, Sch Med, Dept Anat, Tsu, Mie 5140001, Japan Mie Univ Tsu Mie Japan 5140001 ch Med, Dept Anat, Tsu, Mie 5140001, Japan
Titolo Testata:
NEUROREPORT
fascicolo: 5, volume: 12, anno: 2001,
pagine: 1027 - 1030
SICI:
0959-4965(20010417)12:5<1027:IDOLDI>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEURONS; LOCALIZATION; GLYCINE; ASTROCYTES; ASPARTATE; PROTEIN; RELEASE;
Keywords:
amino acid; neurotrophic factor; serine;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Semba, R Mie Univ, Sch Med, Dept Anat, Edobashi 2-174, Tsu, Mie 5140001, Japan Mie Univ Edobashi 2-174 Tsu Mie Japan 5140001 Mie 5140001, Japan
Citazione:
E. Yasuda et al., "Immunohistochemical demonstration of L-serine distribution in the rat brain", NEUROREPORT, 12(5), 2001, pp. 1027-1030

Abstract

L-Serine has been suggested by in vitro studies to be an important neurotrophic factor which supports survival and neurite outgrowth of neurons. It is also a precursor of D-serine, a putative neurotransmitter. In the presentstudy, we raised antibodies against L-serine in a rabbit and examined immunohistochemical distribution of the amino acid in the rat brain. In the hippocampus and the cerebellar cortex, where neurotrophic effects of L-serine have been indicated, L-serine immunoreactivity was found primarily in astrocytes. In the brain stem, where neuronal distribution of D-serine was reported, positive staining for L-serine wag located primarily in neurons. Regional differences of cellular distribution of L-serine were indicated. NeuroReport 12:1027-1030 (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 21:51:32