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Titolo:
The classification, genetics and neuropathology of frontotemporal dementia. Introduction to the special topic papers: Part I
Autore:
Hodges, JR; Miller, B;
Indirizzi:
MRC, Cognit & Brain Sci Unit, Cambridge CB2 4EF, England MRC Cambridge England CB2 4EF Brain Sci Unit, Cambridge CB2 4EF, England Addenbrookes Hosp, Univ Dept Neurol, Cambridge CB2 2QQ, England Addenbrookes Hosp Cambridge England CB2 2QQ , Cambridge CB2 2QQ, England UCSF, Mt Zion Hosp, San Francisco, CA 94115 USA UCSF San Francisco CA USA94115 Mt Zion Hosp, San Francisco, CA 94115 USA
Titolo Testata:
NEUROCASE
fascicolo: 1, volume: 7, anno: 2001,
pagine: 31 - 35
SICI:
1355-4794(2001)7:1<31:TCGANO>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
MOTOR-NEURON DISEASE; MULTIPLE SYSTEM TAUOPATHY; PRESENILE-DEMENTIA; TAU-GENE; SUBCORTICAL GLIOSIS; SEMANTIC DEMENTIA; PICKS-DISEASE; PARKINSONISM; DEGENERATION; MUTATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
46
Recensione:
Indirizzi per estratti:
Indirizzo: Hodges, JR MRC, Cognit & Brain Sci Unit, 15 Chaucer Rd, Cambridge CB2 4EF,England MRC 15 Chaucer Rd Cambridge England CB2 4EF e CB2 4EF, England
Citazione:
J.R. Hodges e B. Miller, "The classification, genetics and neuropathology of frontotemporal dementia. Introduction to the special topic papers: Part I", NEUROCASE, 7(1), 2001, pp. 31-35

Abstract

Interest in the neuropsychology and neuropsychiatry of frontotemporal dementia (FTD) has escalated in the past decade, as evidenced by the accompanying 10 special topic papers from research groups in the UK, France, North America and Australia addressing a wide range of theoretical and clinical issues. The first part of this review deals with the confusing terminologies that have been used in the area and argues for the retention of the term FTDas the general clinical label, with further subcategorization into the three principal clinical syndromes seen at presentation: frontal variant FTD (often called dementia of frontal type), semantic dementia and progressive non-fluent aphasia, Each of these syndromes has a characteristic profile of presenting clinical features, but may be accompanied by any one of five types of non-Alzheimer pathological change. There have also been significant advances in the genetics of FTD with the identification of tau gene mutations on chromosome 17 in some familial cases, The remarkable story of the discovery of these, the tau gene mutations, is briefly described. Part II of this review (Hodges and Miller, 2001) sets the special issue papers within the context of advances in the neuropsychology of frontal variant FTD and semantic dementia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/06/19 alle ore 17:08:10