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Titolo:
Multifunctional strands in tight junctions
Autore:
Tsukita, S; Furuse, M; Itoh, M;
Indirizzi:
Kyoto Univ, Fac Med, Dept Cell Biol, Sakyo Ku, Kyoto 6068501, Japan Kyoto Univ Kyoto Japan 6068501 Cell Biol, Sakyo Ku, Kyoto 6068501, Japan
Titolo Testata:
NATURE REVIEWS MOLECULAR CELL BIOLOGY
fascicolo: 4, volume: 2, anno: 2001,
pagine: 285 - 293
SICI:
1471-0072(200104)2:4<285:MSITJ>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
CANINE KIDNEY-CELLS; CLOSTRIDIUM-PERFRINGENS ENTEROTOXIN; POLARIZED EPITHELIAL-CELLS; DOMAIN-CONTAINING PROTEINS; TUMOR-SUPPRESSOR PROTEIN; ADHESION MOLECULE; MEMBRANE-PROTEINS; ENDOTHELIAL-CELLS; IMMUNOGLOBULIN SUPERFAMILY; POSSIBLE INVOLVEMENT;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
104
Recensione:
Indirizzi per estratti:
Indirizzo: Tsukita, S Kyoto Univ, Fac Med, Dept Cell Biol, Sakyo Ku, Kyoto 6068501, Japan Kyoto Univ Kyoto Japan 6068501 Sakyo Ku, Kyoto 6068501, Japan
Citazione:
S. Tsukita et al., "Multifunctional strands in tight junctions", NAT REV MOL, 2(4), 2001, pp. 285-293

Abstract

Tight junctions are one mode of cell-cell adhesion in epithelial and endothelial cellular sheets. They act as a primary barrier to the diffusion of solutes through the intercellular space, create a boundary between the apical and the basolateral plasma membrane domains, and recruit various cytoskeletal as well as signalling molecules at their cytoplasmic surface. New insights into the molecular architecture of tight junctions allow us to now discuss the structure and functions of this unique cell-cell adhesion apparatus in molecular terms.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 11:29:17