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Titolo:
Cesium-133: A potential reporter of the hepatic uptake of contrast agents
Autore:
Colet, JM; Lecomte, S; Vander Elst, L; Muller, RN;
Indirizzi:
Univ Mons, NMR Lab, Dept Organ Chem, B-7000 Mons, Belgium Univ Mons MonsBelgium B-7000 Lab, Dept Organ Chem, B-7000 Mons, Belgium
Titolo Testata:
MAGNETIC RESONANCE IN MEDICINE
fascicolo: 4, volume: 45, anno: 2001,
pagine: 711 - 715
SICI:
0740-3194(200104)45:4<711:CAPROT>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
RAT-LIVER; CS-133; DTPA;
Keywords:
NMR; cesium-133; liver; contrast agent; quantitation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: Muller, RN Univ Mons, NMR Lab, Dept Organ Chem, B-7000 Mons, Belgium Univ Mons Mons Belgium B-7000 rgan Chem, B-7000 Mons, Belgium
Citazione:
J.M. Colet et al., "Cesium-133: A potential reporter of the hepatic uptake of contrast agents", MAGN RES M, 45(4), 2001, pp. 711-715

Abstract

NMR spectroscopy of intracellularly located Cs-133 has been used to monitor the uptake of Gd-EOB-DTPA by the isolated rat liver. As shown by P-31 spectroscopy, accumulation of Cs-133 ions in hepatocytes does not produce detectable effects on the metabolism. The hepatic internalization of Gd-EOB-DTPA was followed by the paramagnetic relaxation enhancement of the intracellular Cs-133 ions, and confirmed by parallel quantitations of Gd and Cs run by inductively coupled plasma (ICP) analysis of liver samples and aliquots of perfusate. The relaxation data significantly underestimate the Gd content, suggesting a potential compartmentation of Cs+ and/or the contrast agent. Magn Reson Med 45:711-715, 2001. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 02:16:09