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Titolo:
Neuroimaging at 1.5 T and 3.0 T: Comparison of oxygenation-sensitive magnetic resonance imaging
Autore:
Kruger, G; Kastrup, A; Glover, GH;
Indirizzi:
Stanford Univ, Dept Radiol, Lucas MRS Ctr, Palo Alto, CA 94305 USA Stanford Univ Palo Alto CA USA 94305 cas MRS Ctr, Palo Alto, CA 94305 USA
Titolo Testata:
MAGNETIC RESONANCE IN MEDICINE
fascicolo: 4, volume: 45, anno: 2001,
pagine: 595 - 604
SICI:
0740-3194(200104)45:4<595:NA1TA3>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
NMR RELAXATION-TIMES; BOLD FUNCTIONAL MRI; HUMAN VISUAL-CORTEX; HUMAN-BRAIN; FIELD-STRENGTH; BLOOD-FLOW; ACTIVATION; DEPENDENCE; CONTRAST; TESLA;
Keywords:
neuroimaging; spiral scan; magnetic field strength; CNR; SNR; physiological noise;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Kruger, G Stanford Univ, Dept Radiol, Lucas MRS Ctr, Palo Alto, CA 94305 USA Stanford Univ Palo Alto CA USA 94305 r, Palo Alto, CA 94305 USA
Citazione:
G. Kruger et al., "Neuroimaging at 1.5 T and 3.0 T: Comparison of oxygenation-sensitive magnetic resonance imaging", MAGN RES M, 45(4), 2001, pp. 595-604

Abstract

Noise properties, the signal-to-noise ratio (SNR), contrast-to-noise ratio(CNR), and signal responses were compared during functional activation of the human brain at 1.5 and 3.0 T. At the higher field spiral gradient-echo (GRE) brain images revealed an average gain in SNR of 1.7 in fully relaxed and 2.2 in images with a repetition time (TR) of 1.5 sec. The tempered gainat longer Tps reflects the fact that the physiological noise depends on the signal strength acid becomes a larger fraction of the total noise at 3.0 T, Activation of the primary motor and visual cortex resulted in a 36% and 44% increase of "activated pixels" at 3.0 T, which reflects a greater sensitivity for the detection of activated gray matter at the higher field, The gain in the CNR exhibited a dependency on the underlying tissue, i.e., an Increase of 1.8x in regions of particular high activation-induced signal changes (presumably venous vessels) and of 2.2x in the average activated areas. These results demonstrate that 3.0 T provides a clear advantage over 1.5 T for neuroimaging of homogeneous brain tissue, although stronger physiological noise contributions, more complicated signal features in the proximityof strong susceptibility gradients, and changes In the intrinsic relaxation times may mediate the enhancement. Magn Reson Med 45:595-604, 2001, (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 00:41:59