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Titolo:
Comparative effects of aging in men and women on the properties of the arterial tree
Autore:
Smulyan, H; Asmar, RG; Rudnicki, A; London, GM; Safar, ME;
Indirizzi:
State Univ New York, Upstate Med Univ, Syracuse, NY USA State Univ New York Syracuse NY USA , Upstate Med Univ, Syracuse, NY USA Inst Cardiovasc, Paris, France Inst Cardiovasc Paris FranceInst Cardiovasc, Paris, France Covance, Malmaison, France Covance Malmaison FranceCovance, Malmaison, France Ctr Hosp FH Manhes, Fleury Merogis, France Ctr Hosp FH Manhes Fleury Merogis France Manhes, Fleury Merogis, France Broussais Hosp, Paris, France Broussais Hosp Paris FranceBroussais Hosp, Paris, France
Titolo Testata:
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
fascicolo: 5, volume: 37, anno: 2001,
pagine: 1374 - 1380
SICI:
0735-1097(200104)37:5<1374:CEOAIM>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
RENIN-ANGIOTENSIN SYSTEM; BLOOD-PRESSURE; PULSE PRESSURE; POSTMENOPAUSAL WOMEN; CARDIOVASCULAR MORTALITY; MYOCARDIAL-INFARCTION; BODY HEIGHT; MENOPAUSE; ESTROGEN; POPULATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Smulyan, H Upstate Med Univ, Univ Hosp, 750 E Adams St, Syracuse, NY 13210USA Upstate Med Univ 750 E Adams St Syracuse NY USA 13210 13210 USA
Citazione:
H. Smulyan et al., "Comparative effects of aging in men and women on the properties of the arterial tree", J AM COL C, 37(5), 2001, pp. 1374-1380

Abstract

OBJECTIVES We measured the properties of the arterial tree, seeking differences between men and women as they aged. BACKGROUND There are many differences between men and women, besides menopause, which might account for such disparities. These include body height, heart rate, stroke volume and smaller arterial diameters. Any gender differences in arterial stiffness could influence pulse pressure (PP), now recognized as a cardiovascular risk factor. METHODS A total of 530 patients (347 men and 183 women) were classified byage into quartiles: less than or equal to 40, 41-47, 48-54 and greater than or equal to 55 years. The middle groups represented the menopausal years. Studies included brachial artery blood pressure (RP), aortic pulse wave velocity (PWV), B-mode ultrasonography and wave form analysis of the common carotid artery (CCA), with its conversion to the aortic wave form. Standard echocardiography provided left ventricular dimensions and flows. Calculatedvalues included CCA compliance and distensibility, systemic compliance, stroke volume and peripheral resistance. RESULTS At all ages, women had higher heart rates but lower BP than men. Pulse pressure, however, was lower in young women and higher in older women. Measurements influenced by body size, such as CCA diameter, compliance andsystemic compliance, were lower in women. Those related to arterial wall properties, such as CCA and aortic distensibility, were the same. Although aortic PWV rose similarly with aging, PWV had more of an influence on PP in women than did mean BP. The reverse was true in men. CONCLUSIONS Despite lower mean BP and similar arterial distensibility, women develop a higher degree of pulsatility with aging, as compared with men. This is mainly due to their smaller physical characteristics, independent of the role of menopause and its related hormonal changes, (J Am Coll Cardiol 2001;37:1374-80) (C) 2001 by the American College of Cardiology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/02/20 alle ore 14:03:17