Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Factor analysis of essential and toxic elements in human placentas from deliveries in artic and subarctic areas of Russia and Norway
Autore:
Odland, JO; Nieboer, E; Romanova, N; Thomassen, Y; Hofoss, D; Lund, E;
Indirizzi:
Univ Tromso, Inst Community Med, N-9037 Tromso, Norway Univ Tromso Tromso Norway N-9037 st Community Med, N-9037 Tromso, Norway Natl Inst Occupat Hlth, Oslo, Norway Natl Inst Occupat Hlth Oslo NorwayNatl Inst Occupat Hlth, Oslo, Norway McMaster Univ, Dept Biochem, Hamilton, ON, Canada McMaster Univ Hamilton ON Canada niv, Dept Biochem, Hamilton, ON, Canada
Titolo Testata:
JOURNAL OF ENVIRONMENTAL MONITORING
fascicolo: 2, volume: 3, anno: 2001,
pagine: 177 - 184
SICI:
1464-0325(2001)3:2<177:FAOEAT>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
ARCTIC POPULATIONS; KOLA-PENINSULA; BIRTH-WEIGHT; BLOOD LEAD; NICKEL; EXPOSURE; CADMIUM; IRON; SYNCYTIOTROPHOBLAST; INDICATOR;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Odland, JO Univ Tromso, Inst Community Med, N-9037 Tromso, Norway Univ Tromso Tromso Norway N-9037 y Med, N-9037 Tromso, Norway
Citazione:
J.O. Odland et al., "Factor analysis of essential and toxic elements in human placentas from deliveries in artic and subarctic areas of Russia and Norway", J ENVIR MON, 3(2), 2001, pp. 177-184

Abstract

Concentrations in human placenta of 11 essential elements (P, Ca, Mg, Cu, S, Na, Fe, Zn, K, Se, Mn) and 5 toxic elements (Ba, Sr, Pb, Ni, Cd) are compared for each of two arctic communities in eastern Norway and western Russia, and for another in each country located at more southerly latitudes. All but Mg, Fe, P and K were present in higher concentrations in the Russian study group. The observed inter-element correlations are reflected by the four major factors identified in a principal component analysis. The total variation explained was 67.3%, of which more than half (35.3%) was contributed by Factor 1. P, Ca, Mg, Ba, Sr, Pb, and Ni were major contributors to this factor. The placental concentrations of these elements depended stronglyon gestational age, increasing from about week 35 and peaking near weeks 39 and 40, and exhibited skewed frequency distributions and a dependence on maternal smoking. The gestational-dependent mineralization of the placenta is interpreted to reflect the deposition of metal phosphates coinciding with smoking-induced tissue damage. The loadings of the remaining three factors are reviewed in the context of common uptake mechanisms, similar biochemistries and unique transport pathways. The inter-element relationships and grouping of the elements observed should constitute a scientific base for the use of placenta composition in environmental monitoring and epidemiological studies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 17:41:28