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Titolo:
Relationships between personality disorders and anthropometry, hormones and metabolism in women
Autore:
Rosmond, R; Baghei, F; Holm, G; Bjorntorp, P;
Indirizzi:
Univ Gothenburg, Dept Heart & Lung Dis, Sahlgrens Univ Hosp, S-41345 Gothenburg, Sweden Univ Gothenburg Gothenburg Sweden S-41345 sp, S-41345 Gothenburg, Sweden
Titolo Testata:
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
fascicolo: 3, volume: 24, anno: 2001,
pagine: 159 - 165
SICI:
0391-4097(200103)24:3<159:RBPDAA>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
BODY-FAT DISTRIBUTION; DEXAMETHASONE SUPPRESSION TEST; OBSESSIVE-COMPULSIVE DISORDER; PSYCHIATRIC ILL-HEALTH; MIDDLE-AGED MEN; ABDOMINAL OBESITY; INSULIN-RESISTANCE; CORTISOL SECRETION; DISEASE; ENDOCRINE;
Keywords:
personality disorders; abdominal obesity; hormones; metabolism; women;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Rosmond, R Univ Gothenburg, Dept Heart & Lung Dis, Sahlgrens Univ Hosp, S-41345 Gothenburg, Sweden Univ Gothenburg Gothenburg Sweden S-41345 Gothenburg, Sweden
Citazione:
R. Rosmond et al., "Relationships between personality disorders and anthropometry, hormones and metabolism in women", J ENDOC INV, 24(3), 2001, pp. 159-165

Abstract

This study sought to examine the potential influence of personality disorders (PD) on anthropometry, hormones and metabolism in women. In a population sample of women born in 1956 (no.=270), estimates of PD:s by Structured Clinical Interview for DSM-III-R, Axis II, were correlated with anthropometric, endocrine, and metabolic factors. The PD:s were grouped into three thematic clusters: cluster A (characterized by oddness or eccentricity), cluster B (characterized by self-centeredness, emotionality, and erratic behavior) and cluster C (characterized by anxiety and fear). Subjects with cluster A PD:s had significantly increased body mass index (BMI, kg/m(2)) and abdominal sagittal diameter (cm) as well as lower salivary cortisol after dexamethasone (DEX) compared to controls. Subjects with cluster B also had a significantly higher abdominal sagittal diameter and significantly lower salivary cortisol levels after DEX than controls. In addition, subjects with cluster B PD:s had decreased levels of ACTH, and significantly higher concentrations of lactate and triglycerides, while high-density lipoprotein (HDL) cholesterol was significantly lower compared to controls. A significantly higher waist/hip ratio was seen among subjects with cluster C PD:s. In addition, these subjects had higher levels of insulin, glucose, lactate, triglycerides, total cholesterol and low-density lipoprotein (LDL) cholesterol than controls. Moreover, IGF-I and HDL cholesterol were significantly decreased in the former group. These results suggest that PD:s are involved in the development of obesity and abdominal fat accumulation in women, with different endocrine and metabolic profiles depending on the type of PD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 00:40:46