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Titolo:
Optical mapping approaches to cardiac electrophysiological functions
Autore:
Sakai, T; Kamino, K;
Indirizzi:
Tokyo Med & Dent Univ, Grad Sch, Dept Physiol, Bunkyo Ku, Tokyo 1138519, Japan Tokyo Med & Dent Univ Tokyo Japan 1138519 unkyo Ku, Tokyo 1138519, Japan Tokyo Med & Dent Univ, Fac Med, Bunkyo Ku, Tokyo 1138519, Japan Tokyo Med & Dent Univ Tokyo Japan 1138519 unkyo Ku, Tokyo 1138519, Japan JAIC Coll Med Care & Welf Technol, Koriyama, Fukushima 9638834, Japan JAICColl Med Care & Welf Technol Koriyama Fukushima Japan 9638834 Japan
Titolo Testata:
JAPANESE JOURNAL OF PHYSIOLOGY
fascicolo: 1, volume: 51, anno: 2001,
pagine: 1 - 18
SICI:
0021-521X(200102)51:1<1:OMATCE>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
VOLTAGE-SENSITIVE DYES; EMBRYONIC CHICK HEART; ACTION-POTENTIAL PROPAGATION; CHARGE-SHIFT PROBES; GUINEA-PIG HEARTS; ELECTRICAL-ACTIVITY; TRANSMEMBRANE VOLTAGE; PATTERNED GROWTH; CELL-CULTURES; RABBIT HEART;
Keywords:
voltage-sensitive dye; optical recording; electrical activity; heart;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
135
Recensione:
Indirizzi per estratti:
Indirizzo: Sakai, T Tokyo Med & Dent Univ, Grad Sch, Dept Physiol, Bunkyo Ku, Tokyo 1138519, Japan Tokyo Med & Dent Univ Tokyo Japan 1138519 Tokyo 1138519, Japan
Citazione:
T. Sakai e K. Kamino, "Optical mapping approaches to cardiac electrophysiological functions", JPN J PHYSL, 51(1), 2001, pp. 1-18

Abstract

Recently, optical methods for monitoring membrane potential with fast voltage-sensitive dyes have been introduced as a powerful tool for studying cardiac electrical functions. These methods offer two principal advantages over more conventional electrophysiological techniques. One is that optical recordings may be made from very small cells that are inaccessible to microelectrode impalement, and the other is that multiple sites/regions of a preparation can be monitored simultaneously to provide spatially resolved mapping of electrical activity. The former has made it possible to record spontaneous electrical activities in early embryonic precontractile hearts, and the latter has been applied for mapping of the propagation patterns of electrical activities in the cardiac tissue. in this article, optical studies of the electrophysiological function of the vertebrate heart are reviewed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 06:33:03