Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CT and F-18-deoxyglucose (FDG) image fusion for optimization of conformal radiotherapy of lung cancers
Autore:
Giraud, P; Grahek, D; Montravers, F; Carette, MF; Deniaud-Alexandre, E; Julia, F; Rosenwald, JC; Cosset, JM; Talbot, JN; Housset, M; Touboul, E;
Indirizzi:
Inst Curie, Dept Oncol Radiotherapie, F-75248 Paris, France Inst Curie Paris France F-75248 col Radiotherapie, F-75248 Paris, France Hop Tenon, Dept Oncol Radiotherapy, F-75970 Paris, France Hop Tenon Paris France F-75970 Oncol Radiotherapy, F-75970 Paris, France Hop Tenon, Dept Nucl Med, F-75970 Paris, France Hop Tenon Paris France F-75970 non, Dept Nucl Med, F-75970 Paris, France Hop Tenon, Dept Radiol, F-75970 Paris, France Hop Tenon Paris France F-75970 Tenon, Dept Radiol, F-75970 Paris, France
Titolo Testata:
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
fascicolo: 5, volume: 49, anno: 2001,
pagine: 1249 - 1257
SICI:
0360-3016(20010401)49:5<1249:CAF(IF>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON-EMISSION-TOMOGRAPHY; SOLITARY PULMONARY NODULES; MEDIASTINAL LYMPH-NODES; HEAD GAMMA-CAMERA; F-18 FLUORODEOXYGLUCOSE; PET SCAN; BRONCHOGENIC-CARCINOMA; COINCIDENCE MODE; TUMORS; METASTASES;
Keywords:
three-dimensional conformal radiotherapy; computed tomography; F-18-deoxyglucose imaging; lung cancer;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Giraud, P Inst Curie, Dept Oncol Radiotherapie, 26 Rue Ulm, F-75248 Paris,France Inst Curie 26 Rue Ulm Paris France F-75248 -75248 Paris, France
Citazione:
P. Giraud et al., "CT and F-18-deoxyglucose (FDG) image fusion for optimization of conformal radiotherapy of lung cancers", INT J RAD O, 49(5), 2001, pp. 1249-1257

Abstract

Purpose: To validate a computed tomography (CT) and F-18-deoxyglucose (FDG) image fusion procedure and to evaluate its usefulness to facilitate target definition and treatment planning in three-dimensional conformal radiation therapy (3D-CRT) for non-small-cell lung cancer. Methods and Materials: Twelve patients were assessed by CT and FDG-coincidence mode dual-head gamma camera (CDET)before radiotherapy. The patients were placed in a similar position during CT and FDG-CDET. Matching was achieved by minimizing the cost function by 3D translation and rotation between four landmarks drawn on the patient's skin. Virtual simulation was performedfrom image fusion and estimated dose-volume histograms (DVH) were calculated. Results: Quantitative analysis indicated that the matching error was < 5 mm. Fusion of anatomic and metabolic data corrected staging of lymph nodes (N) for 4 patients and staging of metastases for 1 patient. In these 5 patients, DVH revealed that the lung volume irradiated at 20 Gy (VI20) was decreased by an average of 22.8%, and tumor volume irradiated at the 95% isodose(V-95) was increased by 22% and 8% for 2 patients, respectively, and was decreased by an average of 59% for 3 patients after fusion. No difference interms of VI20 and V-95 was observed for the other 7 patients. Conclusion: We have validated CT and FDG-CDET lung image fusion to facilitate determination of lung cancer volumes, which improved the accuracy of 3D-CRT. <(c)> 2001 Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/05/20 alle ore 11:13:49