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Titolo:
Drugs for treatment of Alzheimer's disease
Autore:
Wilkinson, D;
Indirizzi:
Moorgreen Hosp, Memory Assessment & Res Ctr, Southampton SO30 3JB, Hants, England Moorgreen Hosp Southampton Hants England SO30 3JB O30 3JB, Hants, England
Titolo Testata:
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
fascicolo: 2, volume: 55, anno: 2001,
pagine: 129 - 134
SICI:
1368-5031(200103)55:2<129:DFTOAD>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLACEBO-CONTROLLED TRIAL; DOUBLE-BLIND; ACETYLCHOLINE-RECEPTORS; DEMENTIA; METRIFONATE; DONEPEZIL; AGONIST; MALT;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Wilkinson, D Moorgreen Hosp, Memory Assessment & Res Ctr, West End, Southampton SO30 3JB, Hants, England Moorgreen Hosp West End Southampton Hants England SO30 3JB nd
Citazione:
D. Wilkinson, "Drugs for treatment of Alzheimer's disease", INT J CL PR, 55(2), 2001, pp. 129-134

Abstract

Alzheimer's disease is already an international problem of enormous significance, with an estimated 500,000 sufferers in the UK alone. There are currently four licensed compounds available for the symptomatic treatment of mild to moderate Alzheimer's disease, yet there is still considerable debate over their effectiveness. A variety of anti-dementia agents affecting the various aspects of the disease are in development and the debate will continue over the potential rationing of such treatments in the future. Drugs developed from the cholinergic and glutamatergic hypotheses will be discussed,and a number of other potential treatments aimed at reducing the oxidativestress and inflammatory response associated with dementia will be reviewed. The arrival of these new treatments for Alzheimer's disease has focused attention on the management of dementia in general and has provided the catalyst for the widespread development of memory clinics to enable proper assessment of patients with dementing disorders, providing hope for both patients and carers.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 14:31:28