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Titolo:
Tracheal cancer in Denmark: a nationwide study
Autore:
Licht, PB; Friis, S; Pettersson, G;
Indirizzi:
Odense Univ Hosp, Dept Clin Physiol & Nucl Med, DK-5000 Odense, Denmark Odense Univ Hosp Odense Denmark DK-5000 ucl Med, DK-5000 Odense, Denmark Cleveland Clin Fdn, Dept Thorac & Cardiovasc Surg, Cleveland, OH 44195 USACleveland Clin Fdn Cleveland OH USA 44195 c Surg, Cleveland, OH 44195 USA Danish Canc Soc, Inst Canc Epidemiol, Copenhagen, Denmark Danish Canc SocCopenhagen Denmark Canc Epidemiol, Copenhagen, Denmark
Titolo Testata:
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
fascicolo: 3, volume: 19, anno: 2001,
pagine: 339 - 345
SICI:
1010-7940(200103)19:3<339:TCIDAN>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
RADIATION-THERAPY; SURGICAL-MANAGEMENT; PRIMARY-CARCINOMA; PRIMARY TUMORS; NEOPLASMS;
Keywords:
tracheal cancer; cancer registry; nationwide survey;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Licht, PB Odense Univ Hosp, Dept Clin Physiol & Nucl Med, DK-5000 Odense, Denmark Odense Univ Hosp Odense Denmark DK-5000 K-5000 Odense, Denmark
Citazione:
P.B. Licht et al., "Tracheal cancer in Denmark: a nationwide study", EUR J CAR-T, 19(3), 2001, pp. 339-345

Abstract

Objective: Most published series on tracheal cancer reflect single institution experiences. We used the nationwide Danish Cancer Registry to report on characteristics and treatment of tracheal cancers in Denmark. Methods: One hundred and nine cases of primary tracheal cancers were extracted from the registry in the period 1978-1995. The clinical data, histological distribution and treatment modalities were analyzed. The cancers were staged in four groups (stage I-IV) according to size, location and spread. Results: Seventeen cases were diagnosed at autopsy. Ninety-two cases were diagnosed in vivo and 84% of these within 3 months after the first consultation. Sixty-three percent of the cancers were squamous cell carcinomas and only 7% were adenoid cystic carcinomas. The disease was at stage I in 21%, stage II in 23%, stage m in 6% and stage IV in 50%, The majority of the patients received radiotherapy as single treatment. Only nine patients were offered surgery(six were resected and three were found inoperable). The overall survival rates for cases diagnosed in vivo were 1-year 32%, 2-year 20% and 5-year 13%. For the resected patients the 5- and 15-year survival rates were 50%. Conclusions: Tracheal cancers were rare and adenoid cystic carcinomas not as frequent as generally believed, Surgery was rarely offered. A resectabilityrate of only 10% is not adequately explained by selection bias and indicates a nihilistic attitude based on ignorance about surgical treatment of tracheal cancers. A more dedicated and aggressive approach with centralized workup and radical treatment is strongly recommended. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 00:13:04