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Titolo:
Methods used to assess pulmonary deposition and absorption of drugs
Autore:
Mobley, C; Hochhaus, G;
Indirizzi:
Nova SE Univ, Coll Pharm, Dept Pharmaceut Sci, Ft Lauderdale, FL 33328 USANova SE Univ Ft Lauderdale FL USA 33328 Sci, Ft Lauderdale, FL 33328 USA Univ Florida, Coll Pharm, Dept Pharmaceut, Gainesville, FL 32610 USA Univ Florida Gainesville FL USA 32610 armaceut, Gainesville, FL 32610 USA
Titolo Testata:
DRUG DISCOVERY TODAY
fascicolo: 7, volume: 6, anno: 2001,
pagine: 367 - 375
SICI:
1359-6446(20010401)6:7<367:MUTAPD>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN RESPIRATORY-TRACT; POWDER INHALER DEVICES; ISOLATED PERFUSED RAT; METERED-DOSE INHALER; FOR-LUNG-RESEARCH; TRIAMCINOLONE ACETONIDE; FLUTICASONE PROPIONATE; REGIONAL DEPOSITION; CONSENSUS STATEMENT; GAMMA-SCINTIGRAPHY;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
64
Recensione:
Indirizzi per estratti:
Indirizzo: Mobley, C Nova SE Univ, Coll Pharm, Dept Pharmaceut Sci, Ft Lauderdale, FL33328 USA Nova SE Univ Ft Lauderdale FL USA 33328 auderdale, FL 33328 USA
Citazione:
C. Mobley e G. Hochhaus, "Methods used to assess pulmonary deposition and absorption of drugs", DRUG DISC T, 6(7), 2001, pp. 367-375

Abstract

The assessment of pulmonary drug absorption and deposition is becoming increasingly important in drug development. Absorption information can be usedto maximize pulmonary selectivity, to screen drug candidates and to help evaluate the bioequivalence of generic inhalation products. Several methods are available to investigate pulmonary drug absorption and deposition, ranging from in vitro experiments to in vivo pharmacokinetic and pharmacodynamic analyses. In combination, these methods can indicate the fate of an inhaled drug.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 22:37:23