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Titolo:
Intraoperative diagnosis of tanycytic ependymoma: Pitfalls and differential diagnosis
Autore:
Dvoracek, MA; Kirby, PA;
Indirizzi:
Univ Iowa, Coll Med, Dept Pathol, Iowa City, IA 52242 USA Univ Iowa Iowa City IA USA 52242 ed, Dept Pathol, Iowa City, IA 52242 USA
Titolo Testata:
DIAGNOSTIC CYTOPATHOLOGY
fascicolo: 4, volume: 24, anno: 2001,
pagine: 289 - 292
SICI:
8755-1039(200104)24:4<289:IDOTEP>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
CYTOLOGICAL PREPARATIONS; BRAIN BIOPSIES;
Keywords:
central nervous system neoplasms; smear preparations; tanycytic ependymoma; ependymoma; cytology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
13
Recensione:
Indirizzi per estratti:
Indirizzo: Kirby, PA Univ Iowa Hosp & Clin, Dept Pathol, 5239A RCP,200 Hawkins Dr, Iowa City, IA 52242 USA Univ Iowa Hosp & Clin 5239A RCP,200 Hawkins Dr Iowa City IA USA 52242
Citazione:
M.A. Dvoracek e P.A. Kirby, "Intraoperative diagnosis of tanycytic ependymoma: Pitfalls and differential diagnosis", DIAGN CYTOP, 24(4), 2001, pp. 289-292

Abstract

Smear preparations have become increasingly popular in the intraoperative assessment of central nervous system pathology. The cytological features ofa histologically proven tanycytic ependymoma are presented with the pitfalls and differential diagnosis. The smear preparation showed a glial neoplasm composed of cells with long, bipolar glial processes and oval to spindle-shaped nuclei resembling those seen in pilocytic astrocytoma smears. The smear characteristics of an ependymoma usually show remarkably uniform round-to-oval nuclei, fluffy glial processes, and a perivascular nuclear-free zone (pseudorosetting). None of these features were present in our case. The accompanying frozen section showed a fascicular spinel-cell tumor that resembled a schwanomma, a commonly reported misinterpretation of the histology of tanycytic ependymomas on frozen sections. Careful attention to the radiological findings, the surgeon's impression, and the intraoperative smear preparation details should allow one to include this uncommon entity in the differential diagnosis of spinal neoplasms. (C) 2001 Wiley-Liss, Inc.

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Documento generato il 29/01/20 alle ore 19:29:22