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Titolo:
Prevalence and epidemiologic correlates of atypical squamous cells of undetermined significance in women at low risk for cervical cancer
Autore:
Becker, E; Edelweiss, MI; Nonnenmacher, B; Bozzetti, MC;
Indirizzi:
Univ Luterana Brasil, Dept Obstet & Gynecol, Porto Alegre, RS, Brazil UnivLuterana Brasil Porto Alegre RS Brazil ol, Porto Alegre, RS, Brazil
Titolo Testata:
DIAGNOSTIC CYTOPATHOLOGY
fascicolo: 4, volume: 24, anno: 2001,
pagine: 276 - 282
SICI:
8755-1039(200104)24:4<276:PAECOA>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN PAPILLOMAVIRUS INFECTION; INTRAEPITHELIAL NEOPLASIA; DNA; ASSOCIATION; LESIONS; SMEARS;
Keywords:
ASCUS; cytopathology; epidemiology; HPV; cervical cancer;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Becker, E Rua Anita Garibaldi 1160-303, BR-90430000 Porto Alegre, RS, Brazil Rua Anita Garibaldi 1160-303 Porto Alegre RS Brazil BR-90430000 BC
Citazione:
E. Becker et al., "Prevalence and epidemiologic correlates of atypical squamous cells of undetermined significance in women at low risk for cervical cancer", DIAGN CYTOP, 24(4), 2001, pp. 276-282

Abstract

Our aim was to determine the prevalence and epidemiologic correlates of atypical squamous cells of undetermined significance (ASCUS) in a population at low risk for cervical cancer in Porto Alegre, Brazil. Sociodemographic data and gynecological and obstetrical history from 977 women screened at anoutpatient clinic were recorded. Specimens were collected for Papanicolaoucervical cytology, colposcopy, and biopsy (if indicated). Sixty-two (6.3%)patients presented ASCUS. 21 (2.1%) presented low-grade squamous intraepithelial lesions, and 6 (0.6%) presented high-grade lesions. Presence of human papillomavirus (HPV) DNA in cervical cells (odds ratio (OR) = 1.57; confidence interval (CI) 95% = 1.11-2.23), history of HPV infection (OR = 3.12; CI 95% = 1.22-7.96), and becoming sexually active at 18 yr or younger (OR =1.70; CI 95% = 1.15-2.51) were independently associated with ASCUS. ASCUS patients reported HPV infections and presented HPV DNA in cervical cells more often than did patients with normal cytology; therefore, they should be carefully monitored to ensure early detection of cancer precursor lesions and prevention of cervical cancer. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/12/19 alle ore 14:51:44