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Titolo:
Some aspects of biochemistry of myocardial infarction
Autore:
Bing, RJ;
Indirizzi:
Huntington Med Res Inst, Dept Expt Cardiol, Pasadena, CA 91101 USA Huntington Med Res Inst Pasadena CA USA 91101 iol, Pasadena, CA 91101 USA
Titolo Testata:
CELLULAR AND MOLECULAR LIFE SCIENCES
fascicolo: 3, volume: 58, anno: 2001,
pagine: 351 - 355
SICI:
1420-682X(200103)58:3<351:SAOBOM>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
GLUCOSE-INSULIN-POTASSIUM; NITRIC-OXIDE SYNTHASE; GENE-THERAPY; ISCHEMIC MYOCARDIUM; CARDIAC MYOCYTES; FATTY-ACIDS; HEART; CYCLOOXYGENASE; ANGIOGENESIS; REVASCULARIZATION;
Keywords:
infarction; myocardium; nitric oxide; prostacyclin; angiogenesis;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
53
Recensione:
Indirizzi per estratti:
Indirizzo: Bing, RJ Huntington Med Res Inst, Dept Expt Cardiol, 99 N El Molino Ave, Pasadena, CA 91101 USA Huntington Med Res Inst 99 N El Molino Ave Pasadena CA USA 91101
Citazione:
R.J. Bing, "Some aspects of biochemistry of myocardial infarction", CELL MOL L, 58(3), 2001, pp. 351-355

Abstract

This review deals with biochemical changes in infarcted heart muscle. Two main topics are emphasized: changes in substrate metabolism and in myocardial nitric oxide (NO), and prostacyclin and thromboxane formation. Alterations in glucose metabolism in infarcted heart are discussed with special reference to its myocardial utilization in ischemia. The biochemical basis of the increase in NO and prostanoids and the relationship between the enzyme producing nitric oxide (NOS)and cyclooxygenases (COX) responsible for formation of prostanoids are described. The relevance of these findings to clinical conditions and to angiogenesis in heart muscle are stressed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 20:39:37