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Titolo:
Acute renal failure requiring dialysis after percutaneous coronary interventions
Autore:
Gruberg, L; Mehran, R; Dangas, G; Mintz, GS; Waksman, R; Kent, KM; Pichard, AD; Satler, LF; Wu, HS; Leon, MB;
Indirizzi:
Washington Hosp Ctr, Div Cardiol, Washington, DC 20010 USA Washington HospCtr Washington DC USA 20010 iol, Washington, DC 20010 USA Cardiovasc Res Fdn, New York, NY USA Cardiovasc Res Fdn New York NY USACardiovasc Res Fdn, New York, NY USA
Titolo Testata:
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
fascicolo: 4, volume: 52, anno: 2001,
pagine: 409 - 416
SICI:
1522-1946(200104)52:4<409:ARFRDA>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
RADIOGRAPHIC-CONTRAST-AGENT; CRITICALLY-ILL PATIENTS; MEDICAL INTENSIVE-CARE; DIABETES-MELLITUS; RISK-FACTORS; INTRAVASCULAR ULTRASOUND; ARTERY DISEASE; ANGIOPLASTY; ANGIOGRAPHY; DYSFUNCTION;
Keywords:
contrast nephropathy; balloon angioplasty; dialysis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Gruberg, L Washington Hosp Ctr, Div Cardiol, 110 Irving St NW,Suite 4B-1, Washington,DC 20010 USA Washington Hosp Ctr 110 Irving St NW,Suite 4B-1 Washington DC USA 20010
Citazione:
L. Gruberg et al., "Acute renal failure requiring dialysis after percutaneous coronary interventions", CATHET C IN, 52(4), 2001, pp. 409-416

Abstract

Acute renal failure requiring dialysis is a rare but serious complication after percutaneous coronary interventions (PCI), associated with high in-hospital mortality and poor longterm survival. We have analyzed the incidence, resource utilization, short- and long-term outcomes, and predictors of dialysis after percutaneous coronary interventions. We studied 51 consecutivepatients who were not on dialysis on admission and developed acute renal failure that required in-hospital dialysis after PCI in comparison to the 7,690 patients who did not require dialysis after PCl. Patients who required dialysis were older, with a higher incidence of hypertension, diabetes, prior bypass surgery, chronic renal failure. and a significantly lower left ventricular ejection fraction. Despite similar angiographic success, these patients had a higher incidence of in-hospital mortality (27.5% vs. 1.0%, P <0.0001), non-Q-wave myocardial infarction (45.7% vs. 14.6%, P < 0.0001), vascular and bleeding complications, and longer hospitalization. At 1-year follow-up, mortality (54.5% vs. 6.4%, P < 0.0001), myocardial infarction (4.5% vs. 1.6%, P = 0.006), and event-free survival (38.6% vs. 72.0%, P < 0.0001) were significantly worse in patients who required dialysis compared to patients who did not. Multivariate analysis revealed in-hospital dialysis and an increase in baseline serum creatinine levels as the most important predictors of in-hospital and long-term mortality. Thus, acute renal failure that requires dialysis after percutaneous coronary interventions is associated with very high in-hospital and 1-year mortality rates and a dramatic increase in hospital resource utilization. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 01:16:12