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Titolo:
Vertebral involvement in hyperphosphatemic tumoral calcinosis
Autore:
Blay, P; Fernandez-Martinez, JM; Diaz-Lopez, B;
Indirizzi:
Hosp Cent Asturias, Med Oncol Serv, Dept Oncol, E-33006 Oviedo, Spain HospCent Asturias Oviedo Spain E-33006 ept Oncol, E-33006 Oviedo, Spain Hosp Cent Asturias, Dept Radiol, E-33006 Oviedo, Spain Hosp Cent AsturiasOviedo Spain E-33006 pt Radiol, E-33006 Oviedo, Spain Hosp Cent Asturias, Dept Internal Med, Bone & Mineral Res Unit, E-33006 Oviedo, Spain Hosp Cent Asturias Oviedo Spain E-33006 Res Unit, E-33006 Oviedo, Spain
Titolo Testata:
BONE
fascicolo: 3, volume: 28, anno: 2001,
pagine: 316 - 318
SICI:
8756-3282(200103)28:3<316:VIIHTC>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Keywords:
hyperphosphatemia; tumoral calcinosis; bone inflammation; vertebra;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
7
Recensione:
Indirizzi per estratti:
Indirizzo: Blay, P Hosp Cent Asturias, Med Oncol Serv, Dept Oncol, C Julian Claveria S-N, E-33006 Oviedo, Spain Hosp Cent Asturias C Julian Claveria S-N OviedoSpain E-33006 ain
Citazione:
P. Blay et al., "Vertebral involvement in hyperphosphatemic tumoral calcinosis", BONE, 28(3), 2001, pp. 316-318

Abstract

Hyperphosphatemic tumoral calcinosis (HTC) is an inherited metabolic disorder characterized by calcified soft tissue masses and hyperphosphatemia. Besides these typical features, a number of less common manifestations have been reported, all of them related to pathologic calcification of various tissues. We have investigated the case of a woman with hyperphosphatemia, recurrent episodes of lumbar pain, and a positive familial history of HTC, A bone scan showed markedly increased uptake in the lon er lumbar spine. Magnetic resonance imaging showed pathological changes in L5 compatible with an inflammatory reaction and not suggestive of neoplastic process. There was no evidence of infection, trauma, malignancy, or other disease that could cause the lesion. We treated the patient with analgesics and NSAIDs and the pain remitted over a period of 1 week, In a follow-up magnetic resonance imaging 7 months later, the L5 lesion had disappeared completely, A computed tomography scan analysis with a bone window showed a sclerotic area at the L5 vertebral body. We believe that this patient was affected by the syndromeof HTC and that the inflammatory phenomena found in L5 are a manifestationof this disease. (Bone 28:316-318; 2001) (C) 2001 by Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 13:48:07