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Titolo:
The placenta dilemma
Autore:
Fisher, SJ;
Indirizzi:
Univ Calif San Francisco, Dept Stomatol, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA Univ Calif San Francisco, Dept Obstet Gynecol & Reprod Sci, San Francisco,CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 rancisco,CA 94143 USA Univ Calif San Francisco, Dept Anat, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA Univ Calif San Francisco, Dept Pharmaceut Chem, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA Univ Calif San Francisco, Biomed Sci Grad Program, San Francisco, CA 94143USA Univ Calif San Francisco San Francisco CA USA 94143 rancisco, CA 94143USA
Titolo Testata:
SEMINARS IN REPRODUCTIVE MEDICINE
fascicolo: 3, volume: 18, anno: 2000,
pagine: 321 - 326
SICI:
1526-8004(2000)18:3<321:TPD>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONGENITAL CYTOMEGALOVIRUS-INFECTION; SEXUALLY-TRANSMITTED DISEASES; CELL-ADHESION MOLECULE; HUMAN CYTOTROPHOBLASTS; IN-VITRO; EXTRAVILLOUS TROPHOBLAST; ENDOVASCULAR INVASION; EXTRACELLULAR-MATRIX; PREECLAMPSIA; EXPRESSION;
Keywords:
placenta; cytotrophoblast; vasculogenesis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
53
Recensione:
Indirizzi per estratti:
Indirizzo: Fisher, SJ Univ Calif San Francisco, Dept Stomatol, HSW 604, San Francisco, CA 94143 USA Univ Calif San Francisco HSW 604 San Francisco CA USA 94143 USA
Citazione:
S.J. Fisher, "The placenta dilemma", SEMIN REP M, 18(3), 2000, pp. 321-326

Abstract

Despite the critical role the placenta plays in governing the outcome of pregnancy, a great deal remains to be learned about this transient organ. Several factors have contributed to our relative lack of knowledge. Far example, most of the placenta's development, which precedes that of the embryo or fetus, occurs during the first half of pregnancy in humans. Thus, it is difficult to obtain the tissue samples that are required to study relevant time points. In addition, placental anatomy is complex; one of the most interesting parts can be obtained only by biopsy of the uterine wall. Recent analyses of these biopsies, combined with information from cell culture models, revealed the unexpected finding that placental cells that invade the uterus phenocopy many endothelial cell characteristics. This finding has several interesting implications for normal pregnancy and for pregnancy complications that could be related, either directly or indirectly to this phenomenon, such as preeclampsia and cytomegalovirus transmission.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 20:18:57