Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Intracellular signaling in the developing blastocyst as a consequence of the maternal-embryonic dialogue
Autore:
Armant, DR; Wang, J; Liu, ZT;
Indirizzi:
Wayne State Univ, Sch Med, CS Mott Ctr Human Growth & Dev, Dept Obstet & Gynecol, Detroit, MI 48201 USA Wayne State Univ Detroit MI USA 48201 et & Gynecol, Detroit, MI 48201 USA Wayne State Univ, Sch Med, Dept Anat & Cell Biol, Detroit, MI 48201 USA Wayne State Univ Detroit MI USA 48201 & Cell Biol, Detroit, MI 48201 USA
Titolo Testata:
SEMINARS IN REPRODUCTIVE MEDICINE
fascicolo: 3, volume: 18, anno: 2000,
pagine: 273 - 287
SICI:
1526-8004(2000)18:3<273:ISITDB>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
EPIDERMAL GROWTH-FACTOR; LEUKEMIA INHIBITORY FACTOR; MOUSE PREIMPLANTATION EMBRYOS; CALCITONIN-GENE EXPRESSION; IN-VITRO FERTILIZATION; ARG-GLY-ASP; SULFATE PROTEOGLYCAN PERLECAN; EXTRACELLULAR-MATRIX PROTEINS; UTERINE LUMINAL EPITHELIUM; FEMALE REPRODUCTIVE-TRACT;
Keywords:
ovum implantation; trophoblast; signal transduction; growth substances; calcium signaling;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
171
Recensione:
Indirizzi per estratti:
Indirizzo: Armant, DR Wayne State Univ, Sch Med, CS Mott Ctr Human Growth & Dev, DeptObstet & Gynecol, 275 E Hancock Ave, Detroit, MI 48201 USA Wayne State Univ 275 E Hancock Ave Detroit MI USA 48201 201 USA
Citazione:
D.R. Armant et al., "Intracellular signaling in the developing blastocyst as a consequence of the maternal-embryonic dialogue", SEMIN REP M, 18(3), 2000, pp. 273-287

Abstract

The success of blastocyst implantation is dependent on signaling between the embryo and the receptive endometrium. Intercellular signaling molecules,which include hormones, growth factors, and cytokines, have been identified that participate in the maternal-embryonic dialogue. These biologically active molecules may target uterine and/or embryonic tissues in a biochemical cascade that coordinates the two developmental programs during implantation. Two notable uterine products are calcitonin and heparin-binding epidermal growth factor-like growth factor, which are both expressed during the receptive phase of the endometrium in humans and in rodent models. We review data that demonstrate the ability of these molecules to accelerate blastocyst differentiation and delineate the respective intracellular signaling pathways that advance the embryonic developmental program. An understanding ofthe mediators regulating embryonic development in utero and their biochemical mechanisms of the action may provide insights for improvement of embryoculture in vitro prior to blastocyst transfer.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 20:32:01