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Titolo:
Chronic urticaria and Hashimoto's thyroiditis: six case reports.
Autore:
Delevaux, I; Andre, M; Tridon, A; Aumaitre, O;
Indirizzi:
CHU, Serv Med Interne, Hop Gabriel Montpied, F-63003 Clermont Ferrand 1, France CHU Clermont Ferrand France 1 ntpied, F-63003 Clermont Ferrand 1, France
Titolo Testata:
REVUE DE MEDECINE INTERNE
fascicolo: 3, volume: 22, anno: 2001,
pagine: 232 - 237
SICI:
0248-8663(200103)22:3<232:CUAHTS>2.0.ZU;2-#
Fonte:
ISI
Lingua:
FRE
Soggetto:
HISTAMINE-RELEASE; AUTOIMMUNITY; ANGIOEDEMA; IGE; AUTOANTIBODIES; ASSOCIATION;
Keywords:
chronic urticaria; Hashimoto's thyroiditis; antithyroglobulin antibodies; thyroid microsomal antibodies; levothyroxine;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Aumaitre, O CHU, Serv Med Interne, Hop Gabriel Montpied, BP 69, F-63003 Clermont Ferrand 1, France CHU BP 69 Clermont Ferrand France 1 lermont Ferrand 1, France
Citazione:
I. Delevaux et al., "Chronic urticaria and Hashimoto's thyroiditis: six case reports.", REV MED IN, 22(3), 2001, pp. 232-237

Abstract

Purpose. - Chronic urticaria is a common skin disorder. The cause is rarely determined. Autoimmune diseases, particularly autoimmune thyroiditis, have been implicated in the occurrence of chronic urticaria. Methods. - We reviewed clinical records of patients with Hashimoto's disease and chronic urticaria. Results. - In our department, six patients had presented chronic urticariaassociated with Hashimoto's thyroiditis: four patients, of which three treated with L-thyroxine were euthyroid, the other two were hypothyroid. Hashimoto's thyroiditis had been diagnosed for three patients during the investigation of chronic urticaria. Three patients developed chronic urticaria though they were treated with thyroid suppression for Hashimoto's disease. Twoof them had a dramatic improvement with opotherapy. One patient who was euthyroid without treatment improved with hormonal therapy. The fourth patient had a partial remission with thyroid hormones and was cured with corticotherapy. Conclusion. - The mecanism by which thyroid autoimmunity is associated with urticaria is poorly understood. A cross-linking of IgE receptors of mastocytes induced by antithyroid antibodies may be a cause of histamine release. Hormonal therapy may be a potent event for the clinical improvement by the suppression of chronic thyroid stimulation. Assay of thyroid hormone and antithyroid antibodies should be performed in patients with chronic urticaria. Discovery of Hashimoto's thyroiditis with chronic urticaria requires thyroid hormone replacement not only in hypothyroid but also euthyroid patients. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 03:02:28