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Titolo:
An improved MR imaging technique for the visualization of myocardial infarction
Autore:
Simonetti, OP; Kim, RJ; Fieno, DS; Hillenbrand, HB; Wu, E; Bundy, JM; Finn, JP; Judd, RM;
Indirizzi:
Siemens Med Syst Inc, Chicago, IL 60611 USA Siemens Med Syst Inc Chicago IL USA 60611 Syst Inc, Chicago, IL 60611 USA Northwestern Univ, Sch Med, Feinberg Cardiovasc Res Inst, Chicago, IL 60611 USA Northwestern Univ Chicago IL USA 60611 sc Res Inst, Chicago, IL 60611 USA Northwestern Univ, Sch Med, Dept Med, Chicago, IL 60611 USA Northwestern Univ Chicago IL USA 60611 d, Dept Med, Chicago, IL 60611 USA Northwestern Univ, Sch Med, Dept Radiol, Chicago, IL 60611 USA Northwestern Univ Chicago IL USA 60611 Dept Radiol, Chicago, IL 60611 USA Northwestern Univ, Sch Med, Dept Biomed Engn, Chicago, IL 60611 USA Northwestern Univ Chicago IL USA 60611 Biomed Engn, Chicago, IL 60611 USA
Titolo Testata:
RADIOLOGY
fascicolo: 1, volume: 218, anno: 2001,
pagine: 215 - 223
SICI:
0033-8419(200101)218:1<215:AIMITF>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
NUCLEAR MAGNETIC-RESONANCE; LEFT-VENTRICULAR DYSFUNCTION; CORONARY-ARTERY DISEASE; GD-DTPA; GADOLINIUM-DTPA; CONTRAST AGENT; REPERFUSION; PERFUSION; ENHANCEMENT; OCCLUSION;
Keywords:
animals; heart, MR; magnetic resonance (MR), comparative studies; magnetic resonance (MR), contrast enhancement; magnetic resonance (MR), inversion recovery; magnetic resonance (MR), pulse sequences; myocardium, infarction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Simonetti, OP Siemens Med Syst Inc, 448 E Ontario St, Chicago, IL 60611 USA Siemens Med Syst Inc 448 E Ontario St Chicago IL USA 60611 A
Citazione:
O.P. Simonetti et al., "An improved MR imaging technique for the visualization of myocardial infarction", RADIOLOGY, 218(1), 2001, pp. 215-223

Abstract

PURPOSE: To design a segmented inversion-recovery turbo fast low-angle shot (turboFLASH) magnetic resonance (MR) imaging pulse sequence for the visualization of myocardial infarction, compare this technique with other MR imaging approaches in a canine model of ischemic injury, and evaluate its utility in patients with coronary artery disease. MATERIALS AND METHODS: Six dogs and 18 patients were examined. In dogs, infarction was produced and images were acquired by using 10 different pulse sequences. In patients, the segmented turboFLASH technique was used to acquire contrast material-enhanced images 19 days +/- 7 (SD) after myocardial infarction. RESULTS: Myocardial regions of increased signal intensity were observed inall animals and patients at imaging. With the postcontrast segmented turboFLASH sequence, the signal intensity of the infarcted myocardium was 1,080%+/- 214 higher than that of the normal myocardium in dogs-nearly twice that of the next best sequence tested and approximately 10-fold greater than that in previous reports. All 18 patients with myocardial infarction demonstrated high signal intensity at imaging. On average, the signal intensity ofthe high-signal-intensity regions in patients was 485% +/- 43 higher than that of the normal myocardium. CONCLUSION: The segmented inversion-recovery turboFLASH sequence produced the greatest differences In regional myocardial signal intensity in animals. Application of this technique in patients with infarction substantially improved differentiation between injured and normal regions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 19:17:02