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Titolo:
Retroperitoneal laparoscopic surgery and oncological risk
Autore:
Cicco, A; Salomon, L; Saint, F; Hoznek, A; Chopin, D; Abbou, CC;
Indirizzi:
Hop Henri Mondor, Serv Urol, F-94010 Creteil, France Hop Henri Mondor Creteil France F-94010 rv Urol, F-94010 Creteil, France
Titolo Testata:
PROGRES EN UROLOGIE
fascicolo: 1, volume: 11, anno: 2001,
pagine: 8 - 15
SICI:
1166-7087(200102)11:1<8:RLSAOR>2.0.ZU;2-4
Fonte:
ISI
Lingua:
FRE
Soggetto:
PORT-SITE METASTASES; TRANSITIONAL-CELL-CARCINOMA; ABDOMINAL-WALL METASTASES; RADICAL NEPHRECTOMY; CANCER-SURGERY; TUMOR-GROWTH; COLORECTAL-CANCER; RANDOMIZED TRIAL; RAT MODEL; RECURRENCE;
Keywords:
laparoscopy; cancer; recurrence; metastasis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
47
Recensione:
Indirizzi per estratti:
Indirizzo: Cicco, A Hop Henri Mondor, Serv Urol, 51 Ave Marechal Lattre Tassigny, F-94010 Creteil, France Hop Henri Mondor 51 Ave Marechal Lattre Tassigny Creteil France F-94010
Citazione:
A. Cicco et al., "Retroperitoneal laparoscopic surgery and oncological risk", PROG UROL, 11(1), 2001, pp. 8-15

Abstract

Objective: To retrospectively evaluate the development of metastasis at trocar sires, local recurrence and distance metastases associated with retroperitoneal laparoscopic surgery performed in the context of malignant tumour. Methods: From 1994 to 1999, 228 retroperitoneal laparoscopic surgical operations were performed in our centre. Fifty sir operations (24.6%) were performed for malignant tumours and comprised 41 radical nephrectomies and 8 partial nephrectomies for renal tumour and 7 nephro-ureterectomies for upper urinary tract rumours. The pathological stage and surgical margins were correlated with TNM 1997 stage, Postoperative data were obtained by physical and radiological examination performed one month and three months after the operation and then every six months. Metastases at the trocar sire, local recurrences and distant metastases were investigated. The specific progression-free survival was calculated according to the Kaplan-Meier method. Results. The mean follow-up was 24.9 +/- 13.85 months. AII patients had tumour-free surgical margins. No trocar site metastasis was observed. For retroperitoneal laparoscopic radical nephrectomies: one patient developed a local recurrence with liver metastases 9 months after the operation (pT3G2) and died 19.7 months after the operation. One patient with a pT3G3Mrenal tumour at the time of diagnosis riled 23.1 months after radical nephrectomy with no signs of local recurrence. For laparoscopic retroperitoneal nephro-ureterectomies: one patient with apT3G3 lesion developed a local recurrence at 12.1 months and died 26.6 months after surgery. One patient with a pT1G2 tumour developed bone metastases at 9 months and died 29 months after the operation. The recurrence-free survival 54 months was 91% for radical nephrectomies. 71% at 30 months for nephro-ureterectomies and 100% at 49 months for partial nephrectomies. Conclusion: Malignant tumours of the upper urinary tract can be managed byretroperitoneal laparoscopy. The short-term results suggest that this surgical technique is not associated with an increased risk of trocar site metastaes or local recurrence and that recurrence-free survival rates comparable to those reported in series of conventional surgery.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 02:47:29