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Titolo:
Airflow limitation during respiratory syncytial virus lower respiratory tract infection predicts recurrent wheezing
Autore:
Bont, L; Van Aalderen, WMC; Versteegh, J; Brus, F; Draaisma, JTM; Pekelharing-Berghuis, M; Van Diemen-Steenvoorde, RAAM; Kimpen, JLL;
Indirizzi:
Univ Utrecht, Med Ctr, Wilhelmina Childrens Hosp, Dept Pediat Infect Dis, NL-3508 AB Utrecht, Netherlands Univ Utrecht Utrecht Netherlands NL-3508 AB 3508 AB Utrecht, Netherlands Univ Amsterdam, Acad Med Ctr, Emma Childrens Hosp, NL-1105 AZ Amsterdam, Netherlands Univ Amsterdam Amsterdam Netherlands NL-1105 AZ Z Amsterdam, Netherlands Rijnstate Hosp, Dept Pediat, Arnhem, Netherlands Rijnstate Hosp Arnhem Netherlands osp, Dept Pediat, Arnhem, Netherlands St Elisabeth Hosp, Dept Pediat, Tilburg, Netherlands St Elisabeth Hosp Tilburg Netherlands Dept Pediat, Tilburg, Netherlands Diakonessen Hosp, Dept Pediat, Utrecht, Netherlands Diakonessen Hosp Utrecht Netherlands Dept Pediat, Utrecht, Netherlands St Antonius Hosp, Dept Pediat, Nieuwegein, Netherlands St Antonius Hosp Nieuwegein Netherlands Pediat, Nieuwegein, Netherlands
Titolo Testata:
PEDIATRIC INFECTIOUS DISEASE JOURNAL
fascicolo: 3, volume: 20, anno: 2001,
pagine: 277 - 282
SICI:
0891-3668(200103)20:3<277:ALDRSV>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE VIRAL BRONCHIOLITIS; BRONCHIAL REACTIVITY; MILD BRONCHIOLITIS; PULMONARY-FUNCTION; CHILDHOOD ASTHMA; LUNG-FUNCTION; CHILDREN; INFANCY; LIFE; SYMPTOMS;
Keywords:
respiratory syncytial virus; asthma; airflow limitation; risk factor; follow-up;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Kimpen, JLL Univ Utrecht, Med Ctr, Wilhelmina Childrens Hosp, Dept Pediat Infect Dis, POB 85090, NL-3508 AB Utrecht, Netherlands Univ Utrecht POB 85090 Utrecht Netherlands NL-3508 AB erlands
Citazione:
L. Bont et al., "Airflow limitation during respiratory syncytial virus lower respiratory tract infection predicts recurrent wheezing", PEDIAT INF, 20(3), 2001, pp. 277-282

Abstract

Background. Respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) is frequently followed by recurrent wheezing. Thus far no clinical risk factors have been identified to predict which infants will have wheezing episodes subsequent to RSV LRTI. Objective. To determine clinical predictors for airway morbidity after RSVLRTI. Methods. In a 1-year follow-up study we investigated the predictive value of auscultatory findings characteristic of airflow limitation (wheezing) during RSV LRTI for subsequent airway morbidity. Clinical characteristics, including the presence or absence of signs of airflow limitation, of hospitalized infants with RSV LRTI were prospectively recorded during 2 winter epidemics. During a 1-year follow-up period parents of 130 infants recorded daily airway symptoms. Outcome measure. Recurrent wheezing defined as greater than or equal to2 episodes of wheezing. Results. Signs of airflow limitation during RSV LRTI were absent in 47 (36%) infants and present in 83 (64%) infants. Recurrent wheezing was recordedin 10 (21%) infants without signs of airflow limitation and in 51 (61%) with signs of airflow limitation during initial RSV LRTI (relative risk, 0.29, P < 0.001). In a multiple logistic regression model, airflow limitation during initial RSV LRTI proved independent from other clinical parameters, including age, parental history of asthma and smoke exposure. Conclusions. A sign of airflow limitation during RSV LRTI is the first useful clinical predictor for subsequent recurrent wheezing.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/09/20 alle ore 21:43:34