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Titolo:
Expression of the voltage-dependent chloride channel CIC-3 in human nasal tissue
Autore:
Oshima, T; Ikeda, K; Furukawa, M; Suzuki, H; Takasaka, T;
Indirizzi:
Tohoku Univ, Sch Med, Dept Otolaryngol, Aoba Ku, Sendai, Miyagi 9808574, Japan Tohoku Univ Sendai Miyagi Japan 9808574 Ku, Sendai, Miyagi 9808574, Japan
Titolo Testata:
ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES
fascicolo: 2, volume: 63, anno: 2001,
pagine: 82 - 86
SICI:
0301-1569(200103/04)63:2<82:EOTVCC>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
FUNCTIONAL EXPRESSION; RAT COCHLEA; CELLS; PROTEIN; DISEASE; CLONING; CLC-5;
Keywords:
submucosal nasal gland; CIC-3; chloride channel;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Oshima, T Tohoku Univ, Sch Med, Dept Otolaryngol, Aoba Ku, 1-1 Seiryo Machi, Sendai,Miyagi 9808574, Japan Tohoku Univ 1-1 Seiryo Machi Sendai Miyagi Japan 9808574 , Japan
Citazione:
T. Oshima et al., "Expression of the voltage-dependent chloride channel CIC-3 in human nasal tissue", ORL-J OTO R, 63(2), 2001, pp. 82-86

Abstract

In the present study, CIC-3, one of the voltage-dependent chloride channels, was identified in human nasal tissue. In situ hybridization and immunohistochemical investigations demonstrated the localization of CIC-3 in the serous acini and ductal portions of submucosal nasal glands, which are the primary source of nasal secretion. Our data suggest that this channel contributes to nasal secretion via chloride transport. Its dysfunction might lead to abnormal nasal secretion in such pathological states as sinusitis. Copyright (C) 2001 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 10:58:09