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Titolo:
Increased cardiac levels of taurine in cardiomyopathy: the paradoxical benefits of oral taurine treatment
Autore:
Militante, JD; Lombardini, JB;
Indirizzi:
Texas Tech Univ, Hlth Sci Ctr, Dept Pharmacol, Lubbock, TX 79430 USA TexasTech Univ Lubbock TX USA 79430 ept Pharmacol, Lubbock, TX 79430 USA Texas Tech Univ, Hlth Sci Ctr, Dept Ophthalmol, Lubbock, TX 79430 USA Texas Tech Univ Lubbock TX USA 79430 pt Ophthalmol, Lubbock, TX 79430 USA Texas Tech Univ, Hlth Sci Ctr, Dept Visual Sci, Lubbock, TX 79430 USA Texas Tech Univ Lubbock TX USA 79430 pt Visual Sci, Lubbock, TX 79430 USA
Titolo Testata:
NUTRITION RESEARCH
fascicolo: 1-2, volume: 21, anno: 2001,
pagine: 93 - 102
SICI:
0271-5317(200101/02)21:1-2<93:ICLOTI>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONGESTIVE-HEART-FAILURE; DEPENDENT DIABETES-MELLITUS; INDUCED MYOCARDIAL DAMAGE; FRIEDREICHS ATAXIA; ISOPROTERENOL; PATHOGENESIS; HAMSTERS; BLOCKADE; STRESS; IRON;
Keywords:
taurine; congestive heart failure; catecholamine cardiotoxicity; Friedreich's ataxia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Lombardini, JB Texas Tech Univ, Hlth Sci Ctr, Dept Pharmacol, 3601 4th St STOP 6592, Lubbock, TX 79430 USA Texas Tech Univ 3601 4th St STOP 6592 Lubbock TX USA 79430
Citazione:
J.D. Militante e J.B. Lombardini, "Increased cardiac levels of taurine in cardiomyopathy: the paradoxical benefits of oral taurine treatment", NUTR RES, 21(1-2), 2001, pp. 93-102

Abstract

Taurine is an amino acid found in high concentrations in mammalian tissues, however, its function has yet to be fully understood. Certain cellular processes are known to be modulated by taurine, e.g., calcium metabolism, protein phosphorylation, and osmoregulation. Taurine has been used with both experimental and clinical success in treating various cardiovascular diseases. Significantly, treatment with oral taurine has been beneficial in improving signs and symptoms of congestive heart failure. Taurine treatment is safe and inexpensive, and at the very least, taurine may be therapeutically useful as a nutritional supplement in patients with cardiovascular disease. Curiously, certain conditions or models of cardiovascular disease which benefit from taurine treatment exhibit increased levels of taurine in the heart. This article serves to review the various experimental and clinical models which have been used to study the paradoxical benefit of therapy with oral taurine. (C) 2001 Elsevier Science Inc, All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 23:37:29