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Titolo:
Sleep in fibromyalgia patients: clinical and polysomnography pattern.
Autore:
Dauvillers, Y; Touchon, J;
Indirizzi:
Hop Gui de Chauliac, Serv Neurol B, F-34295 Montpellier 5, France Hop Gui de Chauliac Montpellier France 5 , F-34295 Montpellier 5, France CRLC, Inserm E9930, Val Daurel, France CRLC Val Daurel FranceCRLC, Inserm E9930, Val Daurel, France
Titolo Testata:
NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY
fascicolo: 1, volume: 31, anno: 2001,
pagine: 18 - 33
SICI:
0987-7053(200102)31:1<18:SIFPCA>2.0.ZU;2-I
Fonte:
ISI
Lingua:
FRE
Soggetto:
PRIMARY FIBROSITIS SYNDROME; SUBSTANCE-P LEVELS; ALPHA-DELTA SLEEP; NON-REM SLEEP; DOUBLE-BLIND; CONTROLLED TRIAL; RHEUMATOID-ARTHRITIS; CEREBROSPINAL-FLUID; HEALTHY-SUBJECTS; GROWTH-HORMONE;
Keywords:
alpha-delta sleep; fibromyalgia; pain; polysomnography; sleep;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
113
Recensione:
Indirizzi per estratti:
Indirizzo: Dauvillers, Y Hop Gui de Chauliac, Serv Neurol B, 80 Ave Augustin Fliche, F-34295 Montpellier 5, France Hop Gui de Chauliac 80 Ave Augustin Fliche Montpellier France 5
Citazione:
Y. Dauvillers e J. Touchon, "Sleep in fibromyalgia patients: clinical and polysomnography pattern.", NEUROP CLIN, 31(1), 2001, pp. 18-33

Abstract

Fibromyalgia syndrome is a common chronic pain syndrome that is often associated with sleep disturbances characterized by subjective experience of non-restorative sleep. The complaints of sleep disturbances are correlated with polysomnographic features clear abnormalities in the continuity of sleepas well as in the sleep architecture. Sleep-recording abnormalities are characterized by a reduced sleep efficiency with increased number of awakenings, a reduced amount of slow wave sleep and an abnormal alpha wave intrusion in non rapid eye movement, termed alpha-delta sleep. These data were confirmed by spectral analysis of sleep showing an increased EEG power density in the higher frequency band and a reduced EEG power density in the lower frequency bands. Moreover, other microstructural aspects of sleep were modified with high frequency of arousals and alpha-K complex reported, both indicators of fragmented sleep. The fibromyalgia symptoms may relate to a non-restorative sleep disorder associated with the alpha-EEG sleep anomalies. However, alpha-EEG sleep anomaly is non-specific for fibrositis, also seen innormal controls during stage 4 sleep deprivation. Moreover, fibromyalgia patients may also experience primary sleep disorder such as sleep apnea or periodic leg movements. The etiology of this common condition is incompletely understood and the existence of a specific entity of fibromyalgia is still a matter of debate. However, several studies have found abnormal brain metabolism of substances such as serotonin implicated in sleep arousal and pain mechanisms and administration of tricyclic antidepressants and selectiveserotonin reuptake inhibitors may be useful in fibromyalgia. Pain, poor sleep quality and anxiety may contribute to the clinical picture. Several factors such as psychological, environmental, genetic factor, altered serotonin metabolism and altered sleep physiology are involved in the pathogenesis of fibromyalgia. (C) 2001 Editions scientifiques el medicales Elsevier SAS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 02:42:01