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Titolo:
Diagnosis of myoclonus in adults.
Autore:
Vercueil, L; Krieger, J;
Indirizzi:
Hop Univ Grenoble, Serv Neurol, F-38700 La Tronche, France Hop Univ Grenoble La Tronche France F-38700 , F-38700 La Tronche, France Hop Univ Strasbourg, Serv Explorat Fonct Syst Nerveux & Pathol Sommeil, F-67000 Strasbourg, France Hop Univ Strasbourg Strasbourg France F-67000 F-67000 Strasbourg, France
Titolo Testata:
NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY
fascicolo: 1, volume: 31, anno: 2001,
pagine: 3 - 17
SICI:
0987-7053(200102)31:1<3:DOMIA>2.0.ZU;2-I
Fonte:
ISI
Lingua:
FRE
Soggetto:
CORTICAL REFLEX MYOCLONUS; POSTTRAUMATIC MOVEMENT-DISORDERS; HUNTINGTONS-DISEASE; ALZHEIMERS-DISEASE; CORTICOBASAL DEGENERATION; RESPONSIVE PARKINSONISM; EPILEPSY; DYSTONIA; ORIGIN; TREMOR;
Keywords:
diagnosis [review]; myoclonus;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
92
Recensione:
Indirizzi per estratti:
Indirizzo: Vercueil, L Hop Univ Grenoble, Serv Neurol, F-38700 La Tronche, France HopUniv Grenoble La Tronche France F-38700 Tronche, France
Citazione:
L. Vercueil e J. Krieger, "Diagnosis of myoclonus in adults.", NEUROP CLIN, 31(1), 2001, pp. 3-17

Abstract

Myoclonus, defined as shock-like involuntary movement, may be physiological or caused by a very wide variety of hereditary and acquired conditions. Because myoclonus can originate from different disorders and lesions affecting quite varied levels of the central and peripheral nervous systems, it represents from many points of view a diagnostic challenge, Moreover, new entities have been recently individualized, such as cortical tremor, which deserve renewed attention. The aim of this review is to propose a rationale for a diagnostic approach based on clinical and electrophysiological grounds. In this setting, we successively address 1) the clinical features allowinga positive diagnosis of myoclonus; 2) the clinical clues to the etiology; 3) the relevance of the clinical context to the diagnosis; and 4) the contribution of neurophysiology. Differentiating myoclonus from ties, spasm, chorea and dystonia can be difficult, and a careful reappraisal of clinical features allowing precise identification is presented. Moreover, the topographical distribution of myoclonus, the temporal pattern of muscle recruitment, the condition of occurrence and the rhythm of the event, may provide clinical clues relevant to the diagnosis. Myoclonus without associated epilepsy, myoclonus with epilepsy, myoclonus with encephalopathy, parkinsonism and/or dementia represent overlapping clinical categories, although they remainuseful for the diagnostic approach. Using electrophysiology (including back-averaging EEG, MEG, SEP, C-reflex studies) to determine the origin of myoclonus may not allow us to focus on the underlying condition. Indeed, in many instances, the myoclonus is cortical in origin, but the pathology is found elsewhere, (C) 2001 Editions scientifiques et medicales Elsevier SAS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/09/19 alle ore 23:27:04