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Titolo:
Anatomic and functional variability: The effects of filter size in group fMRI data analysis
Autore:
White, T; OLeary, D; Magnotta, V; Arndt, S; Flaum, M; Andreasen, NC;
Indirizzi:
Univ Iowa Hosp & Clin, Mental Hlth Clin Res Ctr, Iowa City, IA 52241 USA Univ Iowa Hosp & Clin Iowa City IA USA 52241 Ctr, Iowa City, IA 52241 USA Univ Iowa Hosp & Clin, Dept Psychiat, Iowa City, IA 52241 USA Univ Iowa Hosp & Clin Iowa City IA USA 52241 iat, Iowa City, IA 52241 USA Univ Iowa Hosp & Clin, Coll Publ Hlth, Iowa City, IA 52241 USA Univ Iowa Hosp & Clin Iowa City IA USA 52241 lth, Iowa City, IA 52241 USA
Titolo Testata:
NEUROIMAGE
fascicolo: 4, volume: 13, anno: 2001,
pagine: 577 - 588
SICI:
1053-8119(200104)13:4<577:AAFVTE>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
EMISSION COMPUTED-TOMOGRAPHY; HUMAN CEREBRAL-CORTEX; HUMAN STRIATE CORTEX; HUMAN VISUAL-CORTEX; HUMAN BRAIN; CENTRAL SULCUS; ELECTRICAL-STIMULATION; MOTOR CORTEX; BLOOD-FLOW; PET IMAGES;
Keywords:
fMRI; group analysis; filter size; spatial resolution;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
59
Recensione:
Indirizzi per estratti:
Indirizzo: White, T Univ Iowa Hosp & Clin, Mental Hlth Clin Res Ctr, Iowa City, IA 52241 USA Univ Iowa Hosp & Clin Iowa City IA USA 52241 City, IA 52241 USA
Citazione:
T. White et al., "Anatomic and functional variability: The effects of filter size in group fMRI data analysis", NEUROIMAGE, 13(4), 2001, pp. 577-588

Abstract

In the analysis of group fMRI scans, an optimal spatial filter should be large enough to accurately blend functionally homologous anatomic regions, yet small enough not to blur the functionally distinct regions. Hanning filters varying from 0.0 to 18.0 mm were evaluated in a group analysis of six healthy controls performing a simple finger-tapping paradigm. Test-retest reliability and Talairach-based measurements of the sensorimotor region were used to explore the optimal filter size. Two distinct regions of functionalactivation were noted in the sensorimotor cortex in group images (n = 6) at both time 1 and time 2. These regions merge once the filter size exceeds approximately 6.0 mm. The original hypothesis that these represented a motor and sensory activation was rejected on the basis of structural and functional variability. A discussion of the inherent difficulties in choosing an appropriate filter size is presented, (C) 2001 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 09:48:32