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Titolo:
Changes in regional cerebral blood flow after electroconvulsive therapy for depression
Autore:
Milo, TJ; Kaufman, GE; Barnes, WE; Konopka, LM; Crayton, JW; Ringelstein, JG; Shirazi, PH;
Indirizzi:
Edward Hines Vet Adm Hosp, Nucl Med Serv, Hines, IL 60141 USA Edward HinesVet Adm Hosp Hines IL USA 60141 ed Serv, Hines, IL 60141 USA Edward Hines Vet Adm Hosp, Psychiat Serv, Hines, IL 60141 USA Edward HinesVet Adm Hosp Hines IL USA 60141 at Serv, Hines, IL 60141 USA
Titolo Testata:
JOURNAL OF ECT
fascicolo: 1, volume: 17, anno: 2001,
pagine: 15 - 21
SICI:
1095-0680(200103)17:1<15:CIRCBF>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
UNIPOLAR DEPRESSION; TOMOGRAPHY; ECT;
Keywords:
depression; electroconvulsive therapy; regional cerebral blood flow; single-photon emission computed tomography; (SPECT); image analysis; Tc-99m hexamethylpropylene amineoxime;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Kaufman, GE Edward Hines Vet Adm Hosp, Nucl Med Serv, Hines, IL 60141 USA Edward Hines Vet Adm Hosp Hines IL USA 60141 es, IL 60141 USA
Citazione:
T.J. Milo et al., "Changes in regional cerebral blood flow after electroconvulsive therapy for depression", J ECT, 17(1), 2001, pp. 15-21

Abstract

Fifteen patients with major depression and normal results of magnetic resonance imaging Or computed tomographic studies were treated by electroconvulsive therapy (ECT). The regional cerebral blood flow (rCBF) of these patients was imaged using Tc-99m hexamethylpropylene amineoxime single-photon emission computed tomography before and after treatment, and their images werecompared with a population of 11 healthy volunteers. Before ECT treatment,the patients had hypoperfusion of the frontal region compared with the controls, and they had multiple areas of altered perfusion throughout the brain. Five of the patients had an excellent clinical response to ECT; these patients also showed changes toward normal in rCBF. The remaining patients had minimal to moderate clinical response and showed no significant change inrCBF. These results indicate that improvement in clinical status as a result of ECT is correlated with a change toward normal in rCBF.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/06/19 alle ore 18:11:18