Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
The spectrum and significance of primary hypophysitis
Autore:
Cheung, CC; Ezzat, S; Smyth, HS; Asa, SL;
Indirizzi:
Univ Toronto, Freeman Ctr Endocrine Oncol, Mt Sinai Hosp, Dept Pathol, Toronto, ON M5G 1X5, Canada Univ Toronto Toronto ON Canada M5G 1X5 athol, Toronto, ON M5G 1X5, Canada Univ Toronto, Freeman Ctr Endocrine Oncol, Mt Sinai Hosp, Dept Med, Toronto, ON M5G 1X5, Canada Univ Toronto Toronto ON Canada M5G 1X5 t Med, Toronto, ON M5G 1X5, Canada Univ Toronto, Freeman Ctr Endocrine Oncol, Mt Sinai Hosp, Dept Surg, Toronto, ON M5G 1X5, Canada Univ Toronto Toronto ON Canada M5G 1X5 Surg, Toronto, ON M5G 1X5, Canada
Titolo Testata:
JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
fascicolo: 3, volume: 86, anno: 2001,
pagine: 1048 - 1053
SICI:
0021-972X(200103)86:3<1048:TSASOP>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
LYMPHOCYTIC HYPOPHYSITIS; DIABETES-INSIPIDUS; GRANULOMATOUS HYPOPHYSITIS; LYMPHOID ADENOHYPOPHYSITIS; CELL ANTIBODIES; PITUITARY-TUMOR; HYPOPITUITARISM; AUTOANTIBODIES; DISEASE; INFUNDIBULONEUROHYPOPHYSITIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: Asa, SL Univ Hlth Network, Dept Pathol, 610 Univ Ave,Suite 4-302, Toronto,ON, Canada Univ Hlth Network 610 Univ Ave,Suite 4-302 Toronto ON Canada nada
Citazione:
C.C. Cheung et al., "The spectrum and significance of primary hypophysitis", J CLIN END, 86(3), 2001, pp. 1048-1053

Abstract

Hypophysitis can present clinically as a mass lesion of the sella turcica. Secondary hypophysitis occurs in cases where a definite etiologic agent orprocess inciting the inflammatory reaction can be identified. In contrast,primary hypophysitis refers to inflammation confined to the pituitary gland with no identifiable etiologic associations. We report three cases of primary hypophysitis to illustrate the spectrum of three clinicopathological entities that encompass this disease: lymphocytic hypophysitis, granulomatous hypophysitis, and xanthomatous hypophysitis. Our three patients underwentsurgery, with variable response. However, conservative, supportive treatment with or without surgical decompression is generally favored over aggressive and extensive surgical resection that results in hypopituitarism. We conclude that the optimal management of patients with hyophysitis requires a high index of suspicion before extensive surgical resection. Histological confirmation of the diagnosis of hypophysitis can be obtained by performing a biopsy or by requesting an intraoperative frozen section consultation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 18:01:17