Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Imaging of skeletal muscle function using (18)FDG PET: force production, activation, and metabolism
Autore:
Pappas, GP; Olcott, EW; Drace, JE;
Indirizzi:
Vet Affairs Palo Alto Hlth Care Syst, Serv Radiol, Diagnost Radiol Ctr 114, Palo Alto, CA 94304 USA Vet Affairs Palo Alto Hlth Care Syst Palo Alto CA USA 94304 CA 94304 USA Stanford Univ, Dept Mech Engn, Biomech Engn Div, Stanford, CA 94305 USA Stanford Univ Stanford CA USA 94305 mech Engn Div, Stanford, CA 94305 USA Stanford Univ, Dept Radiol, Stanford, CA 94305 USA Stanford Univ StanfordCA USA 94305 , Dept Radiol, Stanford, CA 94305 USA
Titolo Testata:
JOURNAL OF APPLIED PHYSIOLOGY
fascicolo: 1, volume: 90, anno: 2001,
pagine: 329 - 337
SICI:
8750-7587(200101)90:1<329:IOSMFU>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON-EMISSION-TOMOGRAPHY; BLOOD-FLOW; GLUCOSE-UPTAKE; INSULIN STIMULATION; EXERCISE; MOTION; MOTOR; HETEROGENEITY; CONTRACTIONS; RELAXATION;
Keywords:
positron emission tomography; fluorodeoxyglucose; intramuscular; tomographic; in vivo;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Drace, JE Vet Affairs Palo Alto Hlth Care Syst, Serv Radiol, Diagnost Radiol Ctr 114, 3801 Miranda Ave, Palo Alto, CA 94304 USA Vet Affairs Palo AltoHlth Care Syst 3801 Miranda Ave Palo Alto CA USA 94304
Citazione:
G.P. Pappas et al., "Imaging of skeletal muscle function using (18)FDG PET: force production, activation, and metabolism", J APP PHYSL, 90(1), 2001, pp. 329-337

Abstract

The purpose of this study was to determine whether [F-18]fluoradeoxyglucose (FDG) positron emission tomography (PET) can be used to evaluate muscle force production, create anatomic images of muscle activity, and resolve thedistribution of metabolic activity within exercising skeletal muscle. Seventeen subjects performed either elbow flexion, elbow extension, or ankle plantar flexion after intravenous injection of FDG. PET imaging was performedsubsequently, and FDG uptake was measured in skeletal muscle far each task. A fivefold increase in resistance during elbow flexion increased FDG uptake in the biceps brachii by a factor of 4.9. Differences in relative FDG uptake were demonstrated as exercise tasks and loads were varied, permitting differentiation of active muscles. The intramuscular distribution of FDG within exercising biceps brachii varied along the transverse and longitudinalaxes of the muscle; coefficients of variation along these axes were 0.39 and 0.23, respectively. These findings suggest FDG PET is capable of characterizing task-specific muscle activity and measuring intramuscular variations of glucose metabolism within exercising skeletal muscle.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 19:03:04