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Titolo:
Baroreceptor modulation of active cutaneous vasodilation during dynamic exercise in humans
Autore:
Mack, GW; Cordero, D; Peters, J;
Indirizzi:
Yale Univ, Sch Med, John B Pierce Lab, New Haven, CT 06515 USA Yale Univ New Haven CT USA 06515 hn B Pierce Lab, New Haven, CT 06515 USA Yale Univ, Sch Med, Dept Epidemiol & Publ Hlth, New Haven, CT 06515 USA Yale Univ New Haven CT USA 06515 iol & Publ Hlth, New Haven, CT 06515 USA
Titolo Testata:
JOURNAL OF APPLIED PHYSIOLOGY
fascicolo: 4, volume: 90, anno: 2001,
pagine: 1464 - 1473
SICI:
8750-7587(200104)90:4<1464:BMOACV>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
SKIN BLOOD-FLOW; BODY NEGATIVE-PRESSURE; MUSCLE VASOCONSTRICTION; REFLEX CONTROL; LEG EXERCISE; TEMPERATURE; MECHANISMS; RESPONSES; SUDOMOTOR; NERVES;
Keywords:
skin circulation; sweating; blood pressure;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Mack, GW Yale Univ, Sch Med, John B Pierce Lab, 290 Congress Ave, New Haven, CT 06515 USA Yale Univ 290 Congress Ave New Haven CT USA 06515 n, CT 06515 USA
Citazione:
G.W. Mack et al., "Baroreceptor modulation of active cutaneous vasodilation during dynamic exercise in humans", J APP PHYSL, 90(4), 2001, pp. 1464-1473

Abstract

The hypothesis that baroreceptor unloading during dynamic limits cutaneousvasodilation by withdrawal of active vasodilator activity was tested in seven human subjects. Increases in forearm skin blood flow (laser-Doppler velocimetry) at skin sites with (control) and without a-adrenergic vasoconstrictor activity (vasodilator only) and in arterial blood pressure (noninvasive) were measured and used to calculate cutaneous vascular conductance (CVC). Subjects performed two similar dynamic exercise (119 +/- 8 W) protocols with and without baroreceptor unloading induced by application of -40 mmHg lower body negative pressure (LBNP). The LBNP condition was reversed (i.e., either removed or applied) after 15 min while exercise continued for an additional 15 min. During exercise without LBNP, the increase in body core temperature (esophageal temperature) required to elicit active cutaneous vasodilation averaged 0.25 +/- 0.08 and 0.31 +/- 0.10 degreesC (SE) at control and vasodilator-only skin sites, respectively, and increased to 0.44 +/- 0.10 and 0.50 +/- 0.10 degreesC (P < 0.05 compared with without LBNP) during exercise with LBNP. During exercise baroreceptor unloading delayed the onsetof cutaneous vasodilation and limited peak CVC at vasodilator-only skin sites. These data support the hypothesis that during exercise baroreceptor unloading modulates active cutaneous vasodilation.

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Documento generato il 04/04/20 alle ore 14:45:58